1.E.52 The Flp/Fap Pilin Putative Holin (FFPP-Hol) Family

The FFPP family is a large diverse family with members from many bacterial phyla.  Some members are annotated as Flp or Fap pilin subunits; others are identified as Holin BlyA family members.  They have sizes of 50 - 80 aas with a single N-terminal TMS although one member has 99 aas and 2 TMSs.  Flp homologues are included in TCDB under TC# 3.A.7.13.1 (pXO1-63) and TC# 3.A.7.15.1 (Flp-1).  Their precise functions appear to be unknown.



This family belongs to the .

Examples:

TC#NameOrganismal TypeExample
1.E.52.1.1

Putative holin, BlyA family

Firmicutes

Putative holin of Ruminococcus obeum

 
1.E.52.1.2

Uncharacterized protein

Firmicutes

Uncharacterized protein of Ruminococcus bromii

 
Examples:

TC#NameOrganismal TypeExample
1.E.52.2.1

Putative holin of 99 aas and 2 TMSs

Actinobacteria

Putative holin of Collinsella intestinalis

 
Examples:

TC#NameOrganismal TypeExample
1.E.52.3.1

Putative holin of 54 aas and 1 TMS

Firmicute

Putative holin of Johnsonella ignava

 
1.E.52.3.2


Flp pilin component

Proteobacteria

Flp pilin compenent of Cupriavidus taiwanensis

 
1.E.52.3.3

Flp/Fap pilin component

δ-Proteobacteria

Pilin compenent of Anaeromyxobacter dehalogenans

 
Examples:

TC#NameOrganismal TypeExample