9.A.5 The Putative Arginine Transporter (ArgW) Family

The putative arginine transporter (ArgW) of Shewanella oneidensis contains 452aas with 10 putative TMSs in a 4+2+4 arrangement and N- and C- termini predicted inside. The Geobacillus homologue, HisW, contains 441aas with 10 or 11 putative TMSs; both N- and C- termini are inside. It is called the COG3314 family or GATE Superfamily (Rodionov et al., 2009).

The reaction believed to be catalyzed by ArgW is:

arginine (out) → arginine (in)



This family belongs to the Leucine-rich Repeat-containing Domain.

 

References:

Ravcheev, D.A., A.A. Best, N. Tintle, M. Dejongh, A.L. Osterman, P.S. Novichkov, and D.A. Rodionov. (2011). Inference of the transcriptional regulatory network in Staphylococcus aureus by integration of experimental and genomics-based evidence. J. Bacteriol. 193: 3228-3240.

Rodionov, D.A., P. Hebbeln, A. Eudes, J. ter Beek, I.A. Rodionova, G.B. Erkens, D.J. Slotboom, M.S. Gelfand, A.L. Osterman, A.D. Hanson, and T. Eitinger. (2009). A novel class of modular transporters for vitamins in prokaryotes. J. Bacteriol. 191: 42-51.

Rodionov, D.A., P.S. Novichkov, E.D. Stavrovskaya, I.A. Rodionova, X. Li, M.D. Kazanov, D.A. Ravcheev, A.V. Gerasimova, A.E. Kazakov, G.Y. Kovaleva, E.A. Permina, O.N. Laikova, R. Overbeek, M.F. Romine, J.K. Fredrickson, A.P. Arkin, I. Dubchak, A.L. Osterman, and M.S. Gelfand. (2011). Comparative genomic reconstruction of transcriptional networks controlling central metabolism in the Shewanella genus. BMC Genomics 12Suppl1: S3.

Examples:

TC#NameOrganismal TypeExample
9.A.5.1.1

The putative arginine uptake porter, ArgP. Regulated by arginine repressor ArgR (Rodionov et al. 2011)

Bacteria

ArgP of Shewanella oneidensis (Q8EHH6)

 
Examples:

TC#NameOrganismal TypeExample
9.A.5.2.1

The putative histidine uptake porter, HutP. Encoded in histidine utilization operons (Ravcheev et al. 2011)

Bacteria

HutP of Geobacillus kaustophilus (Q5L082)

 
9.A.5.2.2

The putative histidine uptake porter, HutP. Encoded in histidine utilization operons and regulated by predicted histidine repressor HutR (Ravcheev et al. 2011)

Bacteria

HutP of Staphylococcus aureus (Q99WQ7)

 
Examples:

TC#NameOrganismal TypeExample
9.A.5.3.1

Sporulation integral membrane protein, YlbJ

Bacteria

YlbJ of Thermincola potens (D5X8Q3)

 
9.A.5.3.2

Sporulation integral membrane protein required for spore cortex formation; trascribed by sigma-E RNA Polymerase (Eichenberger et al., 2003). (408 aas; 10 TMSs; two repeats; Gate Superfamily).

Bacteria

YlbJ of Bacillus subtilis (O34765)

 
Examples:

TC#NameOrganismal TypeExample
9.A.5.4.1

5 TMS homologue of YlbJ (242 aas).

Bacteria

5 TMS YlbJ homologue of Vibrio mimicus (D2YRH2)

 
9.A.5.4.2

The uncharacterized YjiH protein of 227 aas and 4 - 5 TMSs. Putative nucleoside recognition pore and gate family; putative inner membrane transporter.

YjiH of E. coli