9.B.54 The Archaeal/Bacterial 4 TMS Putative DMT (AB-4DMT) Family
The AB-4DMT family includes many small proteins, all of which have 4 TMSs per polypeptide chain. Homology with SMR-like proteins has been considered but not established. Additional bacterial homologues may be found in the B-4DMT Family (TC# 9.B.148). This 4 TMS domain may also be found at the N-terminus of a putative archaeal chloride channel, CLC (TC# 2.A.49.6.4). While homology with the DMT superfamily is not established, it appears that families 9.B.54, 9.B.106, and 9.B.148, all containing 4 TMS members, may be homologous.
Archaeal 4 TMS protein of 171 aas
4DMT protein of Natrialba magadii (Natronobacterium magadii)
SPW repeat protein of 157 aas and 4 TMSs.
UP of Natrialba taiwanensis
Uncharacterized protein of 184 aas and 4 TMSs.
UP of Saccharomonospora marina
SPW repeat protein of 110 aas and 3 or 4 TMSs
SPW repeat protein of Natronococcus jeotgali
Uncharacterized protein of 121 aas and 4 TMSs
UP of Nitrolancea hollandica