TRANSPORTERS FROM HUMANS:
| Transporter Information: | |
| Name: | ATP-binding cassette, sub-family B (MDR/TAP), member 7 |
|---|---|
| Symbol: | ABCB7 |
| TC: | 3.A.1.210.4 |
| Locations: | Xq12-q13 |
| Aliases: | EST140535, Atm1p |
| GenBank: | AF038950 |
| Swiss-Prot: | O75027 |
| Accession Number: | NM_004299 |
| GDB | GDB:7016795 |
| LocusLink | 22 |
| OMIM | 300135 |
| PubMed (9143506): | Savary S, Allikmets R, Denizot F, Luciani MF, Mattei MG, Dean M, Chimini G. Isolation and chromosomal mapping of a novel ATP-binding cassette transporterconserved in mouse and human.Genomics. 1997 Apr 15;41(2):275-8. PMID: 9143506 [PubMed - indexed for MEDLINE] We report here on the identification and genomic mapping of a novel member of the family of the ATP-binding cassette (ABC) transporters, ABC7, conserved in mouse and in humans. The ABC7 gene encodes a protein with the typical features of half-transporters, such as those involved in translocation of antigenic peptides or in peroxisomal disorders. ABC7 shows a ubiquitous expression pattern and maps to the X chromosome both in mouse and in humans. The high sequence similarity to those of two yeast half-transporters supports once again the extreme evolutionary conservation of this family of proteins. |
>sp|O75027|ABC7_HUMAN ATP-binding cassette, sub-family B, member 7, mitochondrial precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein) - Homo sapiens (Human). MALLAMHSWRWAAAAAAFEKRRHSAILIRPLVSVSGSGPQWRPHQLGALGTARAYQIPESLKSITWQRLGKGNSGQFLDA AKALQVWPLIEKRTCWHGHAGGGLHTDPKEGLKDVDTRKIIKAMLSYVWPKDRPDLRARVAISLGFLGGAKAMNIVVPFM FKYAVDSLNQMSGNMLNLSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGF HLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIMFEVMLVSGVLYYKCGAQFALVTLGTLGTYTAFTVAVTRWRTRFRI EMNKADNDAGNAAIDSLLNYETVKYFNNERYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSAIFSVGLTAIMVLASQGI VAGTLTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTQIKDKVMASPLQITPQTATVAFDNVHFE YIEGQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAVLFHN TIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLD SITEETILGAMKDVVKHRTSIFIAHRLSTVVDADEIIVLDQGKVAERGTHHGLLANPHSIYSEMWHTQSSRVQNHDNPKW EAKKENISKEEERKKLQEEIVNSVKGCGNCSC | |