TRANSPORTERS FROM HUMANS:
| Transporter Information: | |
| Name: | potassium inwardly-rectifying channel, subfamily J, member 3 |
|---|---|
| Symbol: | KCNJ3 |
| TC: | 1.A.2.1.3 |
| Locations: | 2q24.1 |
| Aliases: | GIRK1, Kir3.1 |
| GenBank: | U50964 |
| Swiss-Prot: | P48549 |
| Accession Number: | NM_002239 |
| GDB | GDB:278325 |
| LocusLink | 3760 |
| OMIM | 601534 |
| PubMed (8088798): | Stoffel M, Espinosa R 3rd, Powell KL, Philipson LH, Le Beau MM, Bell GI. Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene(KCNJ3): localization to chromosome 2 and identification of a simple tandemrepeat polymorphism.Genomics. 1994 May 1;21(1):254-6. PMID: 8088798 [PubMed - indexed for MEDLINE] The gene encoding the human G-protein-coupled inwardly rectifying potassium channel designated GIRK1 (gene symbol, KCNJ3) was mapped to chromosome 2 by analyzing its segregation in a panel of human-hamster somatic cell hybrids. This assignment was confirmed by fluorescence in situ hybridization to metaphase chromosomes, and the gene was further localized to band 2q24.1. A highly informative simple tandem repeat DNA polymorphism of the form (CA)n was identified and used to localize KCNJ3 within the genetic map of the long arm of chromosome 2. |
>sp|P48549|IRK3_HUMAN G protein-activated inward rectifier potassium channel 1 OS=Homo sapiens GN=KCNJ3 PE=1 SV=1
MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKW
RWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGII
LFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPE
GEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDE
VLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDITTKLP
SKLQKITGREDFPKKLLRMSSTTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGG
AARMEGNLPAKLRKMNSDRFT
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