4.A.3.2.7
N,N'-diacetylchitobiose (cellobiose) PTS permease, CelABC (IIABC). Essential for normal virulence and biofilm formation by K. pneumoniae which causes pyogenic liver abscesses (Wu et al. 2012). 88% identical to the diacetylchitobiose II (4.A.3.2.1) of E. coli. These two proteins are probably orthologous.
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Accession Number: | C4X745 |
Protein Name: | PEP-dependent phosphotransferase enzyme II |
Length: | 452 |
Molecular Weight: | 48426.00 |
Species: | Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 [484021] |
Number of TMSs: | 10 |
Substrate |
N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-aldehydo-D-glucosamine |
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1: MSKVIDSLEK VLLPFAVKIG KQPHINAIKN GFIKLMPLTL AGAMFVLINN VFLSFGEGSF
61: FYSMGIRLDA STIETLNGFK AIGGNVYNGT LGIMSLMAPF FIGSALAEER KVDPMAAGLL
121: AVAAFMTVTP YSVGEAYAVG ANWLGGQNII SGMIIGLVVA ELFTFVIRRN WVIRLPDSVP
181: GSVSRSFSAL IPGFLILSIF GIISWALASY GSNFHQIIMD SISTPLAAMG SVVGWAYVIF
241: NSLLWFFGVH GSLALTALDN GIMTPWALEN IALYNQYGSV DAAIEAGKQF HFWAKPMLDS
301: YILLGGSGAT LGLIIAIFIA SRRADHRQVA KLALPSGIFQ INEPILFGLP IIMNPVMFIP
361: FVLVQPILAA ITLAAYSLGI IPPVTNLAPW TMPTGLGAFF NSNGSVAALL VALFNLGVAT
421: LVYLPFVVLS NKAQTVIEQE ESEEDIANAL KF