1.A.34.1.4 SpoIIQ-SpoIIIAH complex spanning the two membranes of the mother cell and the prespore. Inhibiting SpoIIQ, SpoIIIAA, or SpoIIIAH function apparently prevents the formation of infectious C. difficile spores and thus disease transmission (Fimlaid et al. 2015). spoIIQ or
spoIIIAH mutants that complete engulfment are impaired in
post-engulfment, forespore and mother cell-specific gene expression, in agreement with a channel-like function (Serrano et al. 2016).
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Accession Number: | G6BHQ4 |
Protein Name: | Peptidase, M23 family |
Length: | 222 |
Molecular Weight: | 24657.00 |
Species: | Clostridioides difficile 050-P50-2011 [997828] |
Number of TMSs: | 1 |
Substrate |
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1: MKKKLLEKDG FYLSLFVCVC LLAVGGVWFT NNNVDKLASN KGIMENANKD SEEEIHLIEK
61: DKKDAIPTAT DSKQNLEKAK SKEENKSSTT KLNYIGDKVI RGYSEKEPSY SKTLDVWETH
121: KGVDISCTKG KEVKSLLNGI VVDVFDDEEY GQSVKIKSDN NIVVVYSNLD KNVSVKKEQK
181: VTEGQSLGTV GSTSQIESEE GIHVHLEAYS GEKSIDPMSL IK