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9.A.3.1.2
The multicomponent Retriever-CCC-WASH Complex (formerly called the PDZ domain-containing SNX31-retromer assembly apparatus). The CCC and WASH complexes appear to function in recruitment to the endosomes. Direct cargo binding may be mediated by the COMMDs (McNally and Cullen 2018).  The structure of the membrane-assembled retromer coat has been determined by cryo-electron tomography (Kovtun et al. 2018) (see family description). These two complexes and their functions have been reviewed (Chen et al. 2019).

Accession Number:H3BV68
Protein Name:Esophageal cancer associated protein, isoform CRA_a
Length:712
Molecular Weight:81581.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:2
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MCVDSRSVLP DHFSPENAND TAKETCLNWF FKIASIRELI PRFYVEASIL KCNKFLSKTG 
61:	ISECLPRLTC MIRGIGDPLV SVYARAYLCR VGMEVAPHLK ETLNKNFFDF LLTFKQIHGD 
121:	TVQNQLVVQG VELPSYLPLY PPAMDWIFQC ISYHAPEALL TEMMERCKKL GNNALLLNSV 
181:	MSAFRAEFIA TRSMDFIGMI KECDESGFPK HLLFRSLGLN LALADPPESD RLQILNEAWK 
241:	VITKLKNPQD YINCAEVWVE YTCKHFTKRE VNTVLADVIK HMTPDRAFED SYPQLQLIIK 
301:	KVIAHFHDFS VLFSVEKFLP FLDMFQKESV RVEVCKCIMD AFIKHQQEPT KDPVILNALL 
361:	HVCKTMHDSV NALTLEDEKR MLSYLINGFI KMVSFGRDFE QQLSFYVESR SMFCNLEPVL 
421:	VQLIHSVNRL AMETRKVMKG NHSRKTAAFV RACVAYCFIT IPSLAGIFTR LNLYLHSGQV 
481:	ALANQCLSQA DAFFKAAISL VPEVPKMINI DGKMRPSESF LLEFLCNFFS TLLIVPDHPE 
541:	HGVLFLVREL LNVIQDYTWE DNSDEKIRIY TCVLHLLSAM SQETYLYHID KVDSNDSLYG 
601:	GDSKFLAENN KLCETVMAQI LEHLKTLAKD EALKRQSSLG LSFFNSILAH GDLRNNKLNQ 
661:	LSVNLWHLAQ RHGCADTRTM VKTLEYIKKQ SKQPDMTHLT ELALRLPLQT RT