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1.A.30.1.2
The flagellar motor (smf-dependent) (PomAB; MotXY) (Okabe et al., 2005). PomB interacts with the third TMS of PomA in the Na+-driven polar flagellum (Yakushi et al. 2004). Sodium-powered stators of the flagellar motor can generate torque in the presence of the sodium channel blocker, phenamil, with mutations near the peptidoglycan-binding region of PomB (Ishida et al. 2019). FliL associates with the flagellar stator in the sodium-driven Vibrio motor (Lin et al. 2018). When the ion channel is closed, PomA and PomB interact strongly. When the ion channel opens, PomA interacts less tightly with PomB. The plug and loop between TMSs 1 and 2 regulate activation of the stator, which depends on the binding of sodium ion to the D24 residue of PomB (Nishikino et al. 2019).

Accession Number:O06873
Protein Name:PomA
Length:253
Molecular Weight:27258.00
Species:Vibrio alginolyticus [663]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Na+

Cross database links:

Pfam: PF01618   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0003774 F:motor activity
GO:0008565 F:protein transporter activity
GO:0006935 P:chemotaxis
GO:0001539 P:ciliary or flagellar motility
GO:0015992 P:proton transport

References (1)

[1] “Putative channel components for the fast-rotating sodium-driven flagellar motor of a marine bacterium.”  Asai Y.et.al.   9260952

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDLATLLGLI GGFAFVIMAM VLGGSIGMFV DVTSILIVVG GSIFVVLMKF TMGQFFGATK 
61:	IAGKAFMFKA DEPEDLIAKI VEMADAARKG GFLALEEMEI NNTFMQKGID LLVDGHDADV 
121:	VRAALKKDIA LTDERHTQGT GVFRAFGDVA PAMGMIGTLV GLVAMLSNMD DPKAIGPAMA 
181:	VALLTTLYGA ILSNMVFFPI ADKLSLRRDQ ETLNRRLIMD GVLAIQDGQN PRVIDSYLKN 
241:	YLNEGKRALE IDE