TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


5.A.3.2.1
Anaerobic, respiratory, membrane-bound formate dehydrogenase, FdnGHI. Two protons are consumed in the cytoplasm while two protons are released in the periplasm, contributing to the pmf (Simon et al., 2008).

Accession Number:P0AAJ3
Protein Name:FdnH aka B1475
Length:294
Molecular Weight:32239.00
Species:Escherichia coli [83333]
Location1 / Topology2 / Orientation3: Cell membrane1 / Single-pass membrane protein2
Substrate electron

Cross database links:

DIP: DIP-35836N
RefSeq: AP_002098.1    NP_415992.1   
Entrez Gene ID: 948794   
Pfam: PF09163   
BioCyc: EcoCyc:FDNH-MONOMER    ECOL168927:B1475-MONOMER    MetaCyc:FDNH-MONOMER   
KEGG: ecj:JW1471    eco:b1475   

Gene Ontology

GO:0009326 C:formate dehydrogenase complex
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0051539 F:4 iron, 4 sulfur cluster binding
GO:0009055 F:electron carrier activity
GO:0008863 F:formate dehydrogenase activity
GO:0046872 F:metal ion binding
GO:0009061 P:anaerobic respiration
GO:0022900 P:electron transport chain
GO:0006810 P:transport

References (5)

[1] “Nitrate-inducible formate dehydrogenase in Escherichia coli K-12. I. Nucleotide sequence of the fdnGHI operon and evidence that opal (UGA) encodes selenocysteine.”  Berg B.L.et.al.   1834669
[2] “A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.”  Aiba H.et.al.   9097039
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Molecular basis of proton motive force generation: structure of formate dehydrogenase-N.”  Jormakka M.et.al.   11884747
Structure:
1KQF   1KQG     

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MAMETQDIIK RSATNSITPP SQVRDYKAEV AKLIDVSTCI GCKACQVACS EWNDIRDEVG 
61:	HCVGVYDNPA DLSAKSWTVM RFSETEQNGK LEWLIRKDGC MHCEDPGCLK ACPSAGAIIQ 
121:	YANGIVDFQS ENCIGCGYCI AGCPFNIPRL NKEDNRVYKC TLCVDRVSVG QEPACVKTCP 
181:	TGAIHFGTKK EMLELAEQRV AKLKARGYEH AGVYNPEGVG GTHVMYVLHH ADQPELYHGL 
241:	PKDPKIDTSV SLWKGALKPL AAAGFIATFA GLIFHYIGIG PNKEVDDDEE DHHE