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1.A.30.2.2
The TolA energy-transducing system. TolQ/R (the putative H+ channel) are listed here; TolA is listed under TC# 2.C.1.2.1, together with its auxiliary proteins. The channel is lined by TolR-Asp23, TolQ-Thr145 and TolQ-Thr178.  The Tol-Pal complex, energized by TolQRA, and using the outer membrane proteins, BtuB and OmpF as receptors, is responsible for the uptake of colicin ColE9 and other bacteriocins; in this process, the complex in the outer membrane bridges and immobilizes the complex components in the inner membrane (Rassam et al. 2018). Salmonella Tol-Pal reduces outer membrane glycerophospholipid levels for envelope Hhomeostasis and survival during bacteremia in a process dependent on the TolQR channel (Masilamani et al. 2018).

Accession Number:P0ABV8
Protein Name:Protein tolR
Length:142
Molecular Weight:15383.00
Species:Escherichia coli O157:H7 [83334]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Single-pass type II membrane protein2
Substrate sodium(1+), hydron

Cross database links:

Entrez Gene ID: 917504    957870   
Pfam: PF02472   
KEGG: ece:Z0906    ecs:ECs0773   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0015031 P:protein transport

References (2)

[1] “Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.”  Perna N.T.et.al.   11206551
[2] “Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.”  Hayashi T.et.al.   11258796

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MARARGRGRR DLKSEINIVP LLDVLLVLLL IFMATAPIIT QSVEVDLPDA TESQAVSSND 
61:	NPPVIVEVSG IGQYTVVVEK DRLERLPPEQ VVAEVSSRFK ANPKTVFLIG GAKDVPYDEI 
121:	IKALNLLHSA GVKSVGLMTQ PI