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3.D.3.2.1
Ubiquinol:cytochrome c oxidoreductase

Accession Number:P13272
Protein Name:UCRI aka UQCRFS1
Length:274
Molecular Weight:29547.00
Species:Bos taurus (Bovine) [9913]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1
Substrate hydron

Cross database links:

RefSeq: NP_777238.1   
Entrez Gene ID: 287020   
Pfam: PF00355    PF09165    PF02921   
KEGG: bta:287020   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0070469 C:respiratory chain
GO:0051537 F:2 iron, 2 sulfur cluster binding
GO:0046872 F:metal ion binding
GO:0008121 F:ubiquinol-cytochrome-c reductase activity
GO:0022900 P:electron transport chain
GO:0006810 P:transport

References (11)

[1] “Cloning and sequencing of a cDNA encoding the Rieske iron-sulfur protein of bovine heart mitochondrial ubiquinol-cytochrome c reductase.”  Usui S.et.al.   2157409
[2] “The mitochondrial targeting presequence of the Rieske iron-sulfur protein is processed in a single step after insertion into the cytochrome bc1 complex in mammals and retained as a subunit in the complex.”  Brandt U.et.al.   8386158
[3] “Isolation and amino acid sequence of the 8 kDa DCCD-binding protein of beef heart ubiquinol:cytochrome c reductase.”  Borchart U.et.al.   2996928
[4] “Isolation and amino acid sequence of the 'Rieske' iron sulfur protein of beef heart ubiquinol:cytochrome c reductase.”  Schaegger H.et.al.   3036596
[5] “Structure of a water soluble fragment of the 'Rieske' iron-sulfur protein of the bovine heart mitochondrial cytochrome bc1 complex determined by MAD phasing at 1.5-A resolution.”  Iwata S.et.al.   8736555
[6] “Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria.”  Xia D.et.al.   9204897
[7] “Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex.”  Iwata S.et.al.   9651245
[8] “The crystal structure of mitochondrial cytochrome bc1 in complex with famoxadone: the role of aromatic-aromatic interaction in inhibition.”  Gao X.et.al.   12269811
[9] “Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex.”  Esser L.et.al.   15312779
[10] “Binding of the respiratory chain inhibitor antimycin to the mitochondrial bc1 complex: a new crystal structure reveals an altered intramolecular hydrogen-bonding pattern.”  Huang L.S.et.al.   16024040
[11] “Surface-modulated motion switch: capture and release of iron-sulfur protein in the cytochrome bc1 complex.”  Esser L.et.al.   16924113
Structure:
1BCC   1BE3   1BGY   1L0L   1L0N   1NTK   1NTM   1NTZ   1NU1   1PP9   [...more]

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FASTA formatted sequence
1:	MLSVAARSGP FAPVLSATSR GVAGALRPLV QAAVPATSES PVLDLKRSVL CRESLRGQAA 
61:	GRPLVASVSL NVPASVRYSH TDIKVPDFSD YRRPEVLDST KSSKESSEAR KGFSYLVTAT 
121:	TTVGVAYAAK NVVSQFVSSM SASADVLAMS KIEIKLSDIP EGKNMAFKWR GKPLFVRHRT 
181:	KKEIDQEAAV EVSQLRDPQH DLERVKKPEW VILIGVCTHL GCVPIANAGD FGGYYCPCHG 
241:	SHYDASGRIR KGPAPLNLEV PSYEFTSDDM VIVG