Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.K.1.1.1
Baseplate structural protein complex (GP5 is a lysozyme showing limited similarity to ComA of Neisseria species (3.A.11.2.1)) plus Gp18 tail sheath protein of phage T4. Gp5 (575 aas), the baseplate hub subunit, contains (1) an N-terminal GP5_OB domain, (2) a central lysozyme domain, and (3) a C-terminal domain of ~200 aas with repeat units that resemble BigA (1.B.12.5.5; residues 400-600) and ComA (3.A.11.2.1; residues 400-600). Twenty proteins comprise the entire tail complex of T4. See Rossmann et al. 2004 and Leiman et al. 2010) for tabulation of the properties and evidence concerning the functions of these constituents. gp27 and gp29 may comprise the transmembrane channel (Hu et al. 2015). The tail complex of T4 resembles the type VI protein secretion systems (TC# 3.A.23) of enteric bacteria (Shneider et al. 2013).

Accession Number:P13332
Protein Name:Tail sheath protein Gp18
Length:659
Molecular Weight:71331.00
Species:Enterobacteria phage T4 [10665]
Location1 / Topology2 / Orientation3: Virion1
Substrate deoxyribonucleic acid

Cross database links:

Entrez Gene ID: 1258597   
Pfam: PF04984   

Gene Ontology

GO:0019012 C:virion

References (8)

[1] “Nucleotide sequence of the tail sheath gene of bacteriophage T4 and amino acid sequence of its product.”  Arisaka F.et.al.   2964531
[2] “Bacteriophage T4 genome.”  Miller E.S.et.al.   12626685
[3] “Nucleotide sequence of the tail tube structural gene of bacteriophage T4.”  Arisaka F.et.al.   2963141
[4] “The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria.”  Aksyuk A.A.et.al.   19229296
[5] “Nucleotide sequence of the tail sheath gene of bacteriophage T4 and amino acid sequence of its product.”  Arisaka F.et.al.   2964531
[6] “Bacteriophage T4 genome.”  Miller E.S.et.al.   12626685
[7] “Nucleotide sequence of the tail tube structural gene of bacteriophage T4.”  Arisaka F.et.al.   2963141
[8] “The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria.”  Aksyuk A.A.et.al.   19229296
Structure:
3FO8   3FOA   3FOH   3FOI   3J2M   3J2N     

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MTLLSPGIEL KETTVQSTVV NNSTGTAALA GKFQWGPAFQ IKQVTNEVDL VNTFGQPTAE 
61:	TADYFMSAMN FLQYGNDLRV VRAVDRDTAK NSSPIAGNID YTISTPGSNY AVGDKITVKY 
121:	VSDDIETEGK ITEVDADGKI KKINIPTGKN YAKAKEVGEY PTLGSNWTAE ISSSSSGLAA 
181:	VITLGKIITD SGILLAEIEN AEAAMTAVDF QANLKKYGIP GVVALYPGEL GDKIEIEIVS 
241:	KADYAKGASA LLPIYPGGGT RASTAKAVFG YGPQTDSQYA IIVRRNDAIV QSVVLSTKRG 
301:	EKDIYDSNIY IDDFFAKGGS EYIFATAQNW PEGFSGILTL SGGLSSNAEV TAGDLMEAWD 
361:	FFADRESVDV QLFIAGSCAG ESLETASTVQ KHVVSIGDAR QDCLVLCSPP RETVVGIPVT 
421:	RAVDNLVNWR TAAGSYTDNN FNISSTYAAI DGNHKYQYDK YNDVNRWVPL AADIAGLCAR 
481:	TDNVSQTWMS PAGYNRGQIL NVIKLAIETR QAQRDRLYQE AINPVTGTGG DGYVLYGDKT 
541:	ATSVPSPFDR INVRRLFNML KTNIGRSSKY RLFELNNAFT RSSFRTETAQ YLQGNKALGG 
601:	IYEYRVVCDT TNNTPSVIDR NEFVATFYIQ PARSINYITL NFVATATGAD FDELTGLAG