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1.K.1.1.1
Baseplate structural protein complex (GP5 is a lysozyme showing limited similarity to ComA of Neisseria species (3.A.11.2.1)) plus Gp18 tail sheath protein of phage T4. Gp5 (575 aas), the baseplate hub subunit, contains (1) an N-terminal GP5_OB domain, (2) a central lysozyme domain, and (3) a C-terminal domain of ~200 aas with repeat units that resemble BigA (1.B.12.5.5; residues 400-600) and ComA (3.A.11.2.1; residues 400-600). Twenty proteins comprise the entire tail complex of T4. See Rossmann et al. 2004 and Leiman et al. 2010) for tabulation of the properties and evidence concerning the functions of these constituents. gp27 and gp29 may comprise the transmembrane channel (Hu et al. 2015). The tail complex of T4 resembles the type VI protein secretion systems (TC# 3.A.23) of enteric bacteria (Shneider et al. 2013).

Accession Number:P17172
Protein Name:Gp27
Length:391
Molecular Weight:44389.00
Species:Enterobacteria phage T4 GN=27 PE=1 SV=4 [10665]
Location1 / Topology2 / Orientation3: Virion1
Substrate deoxyribonucleic acid

Cross database links:

RefSeq: NP_049803.1   
Entrez Gene ID: 1258643   
Pfam: PF09097    PF09096   

Gene Ontology

GO:0019012 C:virion
GO:0005515 F:protein binding

References (3)

[1] “Bacteriophage T4 gene 27.”  Bova R.et.al.   2349100
[2] “Bacteriophage T4 genome.”  Miller E.S.et.al.   12626685
[3] “Bacteriophage T4 late gene expression: overlapping promoters direct divergent transcription of the base plate gene cluster.”  Scarlato V.et.al.   2763463
Structure:
1K28   1PDJ   1WTH   2Z6B   5IV5     

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSMLQRPGYP NLSVKLFDSY DAWSNNRFVE LAATITTLTM RDSLYGRNEG MLQFYDSKNI 
61:	HTKMDGNEII QISVANANDI NNVKTRIYGC KHFSVSVDSK GDNIIAIELG TIHSIENLKF 
121:	GRPFFPDAGE SIKEMLGVIY QDRTLLTPAI NAINAYVPDI PWTSTFENYL SYVREVALAV 
181:	GSDKFVFVWQ DIMGVNMMDY DMMINQEPYP MIVGEPSLIG QFIQELKYPL AYDFVWLTKS 
241:	NPHKRDPMKN ATIYAHSFLD SSIPMITTGK GENSIVVSRS GAYSEMTYRN GYEEAIRLQT 
301:	MAQYDGYAKC STIGNFNLTP GVKIIFNDSK NQFKTEFYVD EVIHELSNNN SVTHLYMFTN 
361:	ATKLETIDPV KVKNEFKSDT TTEESSSSNK Q