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5.A.3.2.1
Anaerobic, respiratory, membrane-bound formate dehydrogenase, FdnGHI. Two protons are consumed in the cytoplasm while two protons are released in the periplasm, contributing to the pmf (Simon et al., 2008).

Accession Number:P24183
Protein Name:FdnG aka B1474
Length:1015
Molecular Weight:112963.00
Species:Escherichia coli [83333]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Periplasm1
Substrate electron

Cross database links:

DIP: DIP-9573N
RefSeq: AP_002097.1    NP_415991.1   
Entrez Gene ID: 946035   
Pfam: PF04879    PF00384    PF01568   
BioCyc: EcoCyc:FDNG-MONOMER    MetaCyc:FDNG-MONOMER   
KEGG: ecj:JW1470    eco:b1474   

Gene Ontology

GO:0005737 C:cytoplasm
GO:0009326 C:formate dehydrogenase complex
GO:0016020 C:membrane
GO:0042597 C:periplasmic space
GO:0051539 F:4 iron, 4 sulfur cluster binding
GO:0009055 F:electron carrier activity
GO:0008863 F:formate dehydrogenase activity
GO:0030151 F:molybdenum ion binding
GO:0008430 F:selenium binding
GO:0009061 P:anaerobic respiration
GO:0055114 P:oxidation reduction

References (6)

[1] “Nitrate-inducible formate dehydrogenase in Escherichia coli K-12. I. Nucleotide sequence of the fdnGHI operon and evidence that opal (UGA) encodes selenocysteine.”  Berg B.L.et.al.   1834669
[2] “A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.”  Aiba H.et.al.   9097039
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Export pathway selectivity of Escherichia coli twin arginine translocation signal peptides.”  Tullman-Ercek D.et.al.   17218314
[6] “Molecular basis of proton motive force generation: structure of formate dehydrogenase-N.”  Jormakka M.et.al.   11884747
Structure:
1KQF   1KQG     

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MDVSRRQFFK ICAGGMAGTT VAALGFAPKQ ALAQARNYKL LRAKEIRNTC TYCSVGCGLL 
61:	MYSLGDGAKN AREAIYHIEG DPDHPVSRGA LCPKGAGLLD YVNSENRLRY PEYRAPGSDK 
121:	WQRISWEEAF SRIAKLMKAD RDANFIEKNE QGVTVNRWLS TGMLCASGAS NETGMLTQKF 
181:	ARSLGMLAVD NQARVUHGPT VASLAPTFGR GAMTNHWVDI KNANVVMVMG GNAAEAHPVG 
241:	FRWAMEAKNN NDATLIVVDP RFTRTASVAD IYAPIRSGTD ITFLSGVLRY LIENNKINAE 
301:	YVKHYTNASL LVRDDFAFED GLFSGYDAEK RQYDKSSWNY QLDENGYAKR DETLTHPRCV 
361:	WNLLKEHVSR YTPDVVENIC GTPKADFLKV CEVLASTSAP DRTTTFLYAL GWTQHTVGAQ 
421:	NIRTMAMIQL LLGNMGMAGG GVNALRGHSN IQGLTDLGLL STSLPGYLTL PSEKQVDLQS 
481:	YLEANTPKAT LADQVNYWSN YPKFFVSLMK SFYGDAAQKE NNWGYDWLPK WDQTYDVIKY 
541:	FNMMDEGKVT GYFCQGFNPV ASFPDKNKVV SCLSKLKYMV VIDPLVTETS TFWQNHGESN 
601:	DVDPASIQTE VFRLPSTCFA EEDGSIANSG RWLQWHWKGQ DAPGEARNDG EILAGIYHHL 
661:	RELYQSEGGK GVEPLMKMSW NYKQPHEPQS DEVAKENNGY ALEDLYDANG VLIAKKGQLL 
721:	SSFAHLRDDG TTASSCWIYT GSWTEQGNQM ANRDNSDPSG LGNTLGWAWA WPLNRRVLYN 
781:	RASADINGKP WDPKRMLIQW NGSKWTGNDI PDFGNAAPGT PTGPFIMQPE GMGRLFAINK 
841:	MAEGPFPEHY EPIETPLGTN PLHPNVVSNP VVRLYEQDAL RMGKKEQFPY VGTTYRLTEH 
901:	FHTWTKHALL NAIAQPEQFV EISETLAAAK GINNGDRVTV SSKRGFIRAV AVVTRRLKPL 
961:	NVNGQQVETV GIPIHWGFEG VARKGYIANT LTPNVGDANS QTPEYKAFLV NIEKA