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4.A.2.1.10
The FrwABCD putative transporter of unknown function. FruA is a 3-domain multiphosphoryl transfer protein: EIAni-HPr-IIAFru (Reizer et al., 1995).

Accession Number:P32670
Protein Name:Multiphosphoryl transfer protein 2
Length:833
Molecular Weight:91774.00
Species:Escherichia coli (strain K12) [83333]
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate

Cross database links:

DIP: DIP-10601N
RefSeq: AP_003862.1    YP_026278.1   
Entrez Gene ID: 948437   
Pfam: PF05524    PF00391    PF02896    PF00381    PF00359   
BioCyc: EcoCyc:EG11906-MONOMER   
KEGG: ecj:JW5555    eco:b3947   

Gene Ontology

GO:0005737 C:cytoplasm
GO:0016301 F:kinase activity
GO:0046872 F:metal ion binding
GO:0008965 F:phosphoenolpyruvate-protein phosphotransfer...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...
GO:0016310 P:phosphorylation

References (5)

[1] “Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes.”  Blattner F.R.et.al.   8265357
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Escherichia coli K-12: a cooperatively developed annotation snapshot -- 2005.”  Riley M.et.al.   16397293
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Novel phosphotransferase system genes revealed by bacterial genome analysis -- a gene cluster encoding a unique Enzyme I and the proteins of a fructose-like permease system.”  Reizer J.et.al.   7773398

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MALIVEFICE LPNGVHARPA SHVETLCNTF SSQIEWHNLR TDRKGNAKSA LALIGTDTLA 
61:	GDNCQLLISG ADEQEAHQRL SQWLRDEFPH CDAPLAEVKS DELEPLPVSL TNLNPQIIRA 
121:	RTVCSGSAGG ILTPISSLDL NALGNLPAAK GVDAEQSALE NGLTLVLKNI EFRLLDSDGA 
181:	TSAILEAHRS LAGDTSLREH LLAGVSAGLS CAEAIVASAN HFCEEFSRSS SSYLQERALD 
241:	VRDVCFQLLQ QIYGEQRFPA PGKLTQPAIC MADELTPSQF LELDKNHLKG LLLKSGGTTS 
301:	HTVILARSFN IPTLVGVDID ALTPWQQQTI YIDGNAGAIV VEPGEAVARY YQQEARVQDA 
361:	LREQQRVWLT QQARTADGIR IEIAANIAHS VEAQAAFGNG AEGVGLFRTE MLYMDRTSAP 
421:	GESELYNIFC QALESANGRS IIVRTMDIGG DKPVDYLNIP AEANPFLGYR AVRIYEEYAS 
481:	LFTTQLRSIL RASAHGSLKI MIPMISSMEE ILWVKEKLAE AKQQLRNEHI PFDEKIQLGI 
541:	MLEVPSVMFI IDQCCEEIDF FSIGSNDLTQ YLLAVDRDNA KVTRHYNSLN PAFLRALDYA 
601:	VQAVHRQGKW IGLCGELGAK GSVLPLLVGL GLDELSMSAP SIPAAKARMA QLDSRECRKL 
661:	LNQAMACRTS LEVEHLLAQF RMTQQDAPLV TAECITLESD WRSKEEVLKG MTDNLLLAGR 
721:	CRYPRKLEAD LWAREAVFST GLGFSFAIPH SKSEHIEQST ISVARLQAPV RWGDDEAQFI 
781:	IMLTLNKHAA GDQHMRIFSR LARRIMHEEF RNALVNAASA DAIASLLQHE LEL