TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.11.2.2
The single stranded DNA uptake competence transporter, ComEA/ComEC (Rec2)

Accession Number:P44408
Protein Name:ComEC aka Rec2
Length:788
Molecular Weight:89356.00
Species:Haemophilus influenzae [727]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate ssDNA

Cross database links:

RefSeq: NP_438234.1   
Entrez Gene ID: 950960   
Pfam: PF03772   
BioCyc: HINF71421:HI_0061-MONOMER   
KEGG: hin:HI0061   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0016787 F:hydrolase activity
GO:0030420 P:establishment of competence for transformation
GO:0006810 P:transport

References (2)

[1] “Sequence of the rec-2 locus of Haemophilus influenzae: homologies to comE-ORF3 of Bacillus subtilis and msbA of Escherichia coli.”  Clifton S.W.et.al.   8063112
[2] “Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.”  Fleischmann R.D.et.al.   7542800

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MKLNLITLVV LLIVADLTLL FLPQPLLLPW QVALVIALVL IFLFIFLRRN FLVSLAFFVA 
61:	SLGYFHYSAL SLSQQAQNIT AQKQVVTFKI QEILHQQDYQ TLIATATLEN NLQEQRIFLN 
121:	WKAKEVPQLS EIWQAEISLR SLSARLNFGG FDRQQWYFSK GITAVGTVKS AVKIADVSSL 
181:	RAEKLQQVKK QTEGLSLQGL LIALAFGERA WLDKTTWSIY QQTNTAHLIA ISGLHIGLAM 
241:	GIGFCLARVV QVFFPTRFIH PYFPLVFGVL FALIYAYLAG FSVPTFRAIS ALVFVLFIQI 
301:	MRRHYSPIQF FTLVVGFLLF CDPLMPLSVS FWLSCGAVGC LLLWYRYVPF SLFQWKNRPF 
361:	SPKVRWIFSL FHLQFGLLLF FTPLQLFLFN GLSLSGFLAN FMAVPIYSFL LVPLILFAVF 
421:	TNGTMFSWQL ANKLAEGITG LISVFQGNWL TVSFNLALGL TALCAGIFML IIWNIYREPE 
481:	ISSSNWQIKR AKFFTLNLSK PLLKNERINV LRCSFGIILL CFTILLFKQL SKPTWQVDTL 
541:	DVGQGLATLI VKNGKGILYD TGSSWRGGSM AELEILPYLQ REGIVLEKLI LSHDDNDHAG 
601:	GASTILKAYP NVELITPSRK NYGENYRTFC TAGRDWHWQG LHFQILSPHN VVTRADNSHS 
661:	CVILVDDGKN SVLLTGDAEA KNEQIFARTL GKIDVLQVGH HGSKTSTSEY LLSQVRPDVA 
721:	IISSGRWNPW KFPHYSVMER LHRYKSAVEN TAVSGQVRVN FFQDRLEIQQ ARTKFSPWYA 
781:	RVIGLSKE