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2.A.7.1.9
The spermidine exporter, MdtIJ (MdtIJ = YdgEF) (Higashi et al., 2008).  Catalyzes the export of spermidine and putrescine, and confers resistance to deoxycholate and SDS (Nishino and Yamaguchi 2001). It can be induced by these polyamines and bile salts. Details of the induction mechanism are known (Leuzzi et al. 2015).

Accession Number:P69210
Protein Name:MdtI
Length:109
Molecular Weight:11720.00
Species: [83333]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Spermidine, Deoxycholate, SDS

Cross database links:

RefSeq: AP_002220.1    NP_416116.1   
Entrez Gene ID: 947333   
Pfam: PF00893   
BioCyc: EcoCyc:B1599-MONOMER    ECOL168927:B1599-MONOMER   
KEGG: ecj:JW1591    eco:b1599   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0015606 F:spermidine transmembrane transporter activity
GO:0015848 P:spermidine transport

References (7)

[1] “A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.”  Aiba H.et.al.   9097039
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Analysis of a complete library of putative drug transporter genes in Escherichia coli.”  Nishino K.et.al.   11566977
[5] “Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.”  Drew D.et.al.   11867724
[6] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[7] “Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli.”  Higashi K.et.al.   18039771

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAQFEWVHAA WLALAIVLEI VANVFLKFSD GFRRKIFGLL SLAAVLAAFS ALSQAVKGID 
61:	LSVAYALWGG FGIAATLAAG WILFGQRLNR KGWIGLVLLL AGMIMVKLA