5.B.1.1.12
Superoxide-generating NADPH oxidase with three subunits: B of 698 aas and 6 TMSs, Q86GL4; C of 1142 aas and 6 TMSs, Q54F44; and light chain of 118 aas and 3 TMSs, Q867X6 (Peracino et al. 2022). It may function as a ferric iron or ferric chelate reductase (Peracino et al. 2022).
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| Accession Number: | Q54F44 |
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| Protein Name: | Superoxide-generating NADPH oxidase heavy chain subunit C |
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| Length: | 1142 |
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| Molecular Weight: | 132499.00 |
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| Species: | Dictyostelium discoideum (Slime mold) [44689] |
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| Number of TMSs: | 6 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
NADH |
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1: MEKQKNISIK KFANPLSFPH EFRTNLHKST FLDASLLELP NISVDKTKNE NNFSITDKIL
61: MESLKENEFK IREFIKNQES GNRVLMIDKN SLKELFNIND NQALDLIFNQ YVQSTRPNLI
121: RKSSNSSLNI DLKKEIKKKT KKSRKSFSRN SKLNNNDSKI DDKNDNYIDK INDINNFNSD
181: IEEIFKKKKE IENTLKIPIG GNSFPIPVEF NNNNNNNNNN NNNNNNNYNN NIDNNNNNNN
241: NNNNNNINNC NNNNINNDNN NNNNNDNDNN NINTVDNHDD DIINNSNNFN KNEYPSSNIS
301: PISPKSSISS FPTNLNNSIN NTGSMVSDSL SSCRNSISSS SIDSSVASIP ITIQSIDFED
361: KNIKSDQFKI ISKSNIENTI ETNPIPPFNQ TNNQCEVQLQ SHSLPTILKQ PHIYKSKSFS
421: SSINSNSKIK KIKKSRSFEI ESKINLFDVI NHIYLNLSKV GSEEQKITSV FKLYDIYDKG
481: FISRDDLKEV LNYRTKQNGL KFQDFTMESL IDHIFQQFDK NMDGYIDFEE FKSELTINNE
541: NKVKEKEENT NYNFKEENIG IYTEKESFHS LKRYLKIEGS KLFFISLFFI INSILVITSF
601: LNVHANNKRA IELFGPGVYI TRIAAQLIEF NAAIILMTMC KQLFTMIRNT KFKFLFPVDK
661: YMTFHKLIGY TLIIASFLHT IGWIVGMAVA TGKPDNIFYD CLAPHFKFRP TVWEMIFNSL
721: PGVTGFIMIS FLIIMAILSL KIIRKSNFEL FYYSHHLFIG FYVLLILHGT MGWIRPPTFW
781: KWFIVPGFFY TVDRSFRLFK RTHRVEVLDY CLKNERVINL TFSKPPSFDY KPGQYLLINV
841: PHISKLQWHP FTMTSSPLED KIYVHIRVTG NWTKKLFRWL SIKKQLQQQQ QLYNNIKQQN
901: VLPDGSNFII NNNNNIDQID LEIGLKPFRI NIDGPFGSSS QYALKQKQVI LVGAGIGVSP
961: MASLLKDISL KKQRLQLLNQ GDQIALEQSK NEITTKFGLG NLEKVHFFWL NRDQHSFQWF
1021: EDLLIDISTN GNSNLPKISI NTFNTRVFPK NDVRVFMLWN GLDKLFKAQG LDPTTNLPFK
1081: THWGRPNWDT IFQYYSKKYS GESISVFCCG PSQLSKELYE KCRYYTCLKT GGTKFYFHKE
1141: NF