5.B.1.1.12 Superoxide-generating NADPH oxidase with three subunits: B of 698 aas and 6 TMSs, Q86GL4; C of 1142 aas and 6 TMSs, Q54F44; and light chain of 118 aas and 3 TMSs, Q867X6 (Peracino et al. 2022). It may function as a ferric iron or ferric chelate reductase (Peracino et al. 2022).
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Accession Number: | Q86GL4 |
Protein Name: | Superoxide-generating NADPH oxidase heavy chain subunit B |
Length: | 698 |
Molecular Weight: | 81239.00 |
Species: | Dictyostelium discoideum (Slime mold) [44689] |
Number of TMSs: | 6 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
NADH |
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1: MNEKKELQQE LELQEFQTPK NQQLEKLQEP NGEISSTGNE TSESGISSPP ISQNDNSNNE
61: NESLNITPNK PFVSMQEELQ NLDIENIPIP PTIQTPKIYK NTNNLIHSKN NLSLPISLSQ
121: ENIVKLDKVD IESNDQVNSN TDNNNNTNNN NNTNNNKNEK IGLRSKIFKS KIFIKIRGWW
181: WHRGISTYIM LFYIALNIGV GVHMFYNMYH SDIFKFLGLS FCFSRTAARL INLNSAVILL
241: PVLRNFLSWL RGTIVNNYIP IDKHLNFHKL CAFMLFCCTI IHCVGHYISF KKINDDVLKI
301: DDGKSVAGDY LNININNFPD EKYLFFKSVP GITGHIMLLI LILIVSSSMW RIRRPMFEIF
361: WYVHHLFIPF YILLCFHGYS KILKKDPQSW MWIIAPFILY SIERLIRIAR SKKRVILEKA
421: IMHPSKVLEL RMKRDNDNFN FKPGQYLYLN CPSIAYHEWH PFTITSAPDD PFISVHINIV
481: GNWTRKLFKL LNPDNKLGLI QEDLKSTQNR GKRRILKIDG PFGAPAENFF KYRNLVLIGA
541: GIGVTPFSSI LRHLKNQNDK QTNADENHLK INKIYFIWIS RQKNSFQWFT DILAELENDE
601: RIDSILEIHI FLTGALELDD YAKIKNAQKC HITNLHSKTL FGRPNFRSIF NQLTQLHQRE
661: KIGVFYCGNK ALGKNIIKNC NKFNGKNNCH LIFHKENF