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9.A.60.1.1
The U snRNA export complex including: phosphorylated adaptor for RNA export (PHAX/RNUXA), nuclear cap-binding protein-1/2 (NCBP1/NCBP2), and RAN GTPase (see also 9.A.50).

Accession Number:Q9H814
Protein Name:Phosphorylated adapter RNA export protein
Length:394
Molecular Weight:44403.00
Species:Homo sapiens (Human) [9606]
Location1 / Topology2 / Orientation3: Nucleus1
Substrate small nuclear RNA

Cross database links:

Entrez Gene ID: 51808   
Pfam: PF10258   
KEGG: hsa:51808   

Gene Ontology

GO:0015030 C:Cajal body
GO:0005829 C:cytosol
GO:0003723 F:RNA binding
GO:0034660 P:ncRNA metabolic process
GO:0015031 P:protein transport
GO:0006408 P:snRNA export from nucleus
GO:0000387 P:spliceosomal snRNP assembly

References (9)

[1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[3] “PHAX and CRM1 are required sequentially to transport U3 snoRNA to nucleoli.”  Boulon S.et.al.   15574332
[4] “The evolutionarily conserved region of the U snRNA export mediator PHAX is a novel RNA-binding domain that is essential for U snRNA export.”  Segref A.et.al.   11333016
[5] “Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex.”  Watkins N.J.et.al.   15574333
[6] “ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.”  Matsuoka S.et.al.   17525332
[7] “A quantitative atlas of mitotic phosphorylation.”  Dephoure N.et.al.   18669648
[8] “Initial characterization of the human central proteome.”  Burkard T.R.et.al.   21269460
[9] “Structure and RNA recognition by the snRNA and snoRNA transport factor PHAX.”  Mourao A.et.al.   20430857
Structure:
2XC7     

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MALEVGDMED GQLSDSDSDM TVAPSDRPLQ LPKVLGGDSA MRAFQNTATA CAPVSHYRAV 
61:	ESVDSSEESF SDSDDDSCLW KRKRQKCFNP PPKPEPFQFG QSSQKPPVAG GKKINNIWGA 
121:	VLQEQNQDAV ATELGILGME GTIDRSRQSE TYNYLLAKKL RKESQEHTKD LDKELDEYMH 
181:	GGKKMGSKEE ENGQGHLKRK RPVKDRLGNR PEMNYKGRYE ITAEDSQEKV ADEISFRLQE 
241:	PKKDLIARVV RIIGNKKAIE LLMETAEVEQ NGGLFIMNGS RRRTPGGVFL NLLKNTPSIS 
301:	EEQIKDIFYI ENQKEYENKK AARKRRTQVL GKKMKQAIKS LNFQEDDDTS RETFASDTNE 
361:	ALASLDESQE GHAEAKLEAE EAIEVDHSHD LDIF