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3.A.23.1.1
Type VI secretion system (T6SS) VasA-L + Vca0107-09; + Vca0123 + Vc1416 (Pukatzki et al., 2006; Pukatzki et al., 2007). This secretion system displays antimicrobial properties (Macintyre et al., 2010).  It functions like contractile tails of phage and penetrates cells with a trimeric VgrG spike protein to which are associated PAAR repeat proteins that sharpen the tip of the spike and are released into the cytoplasm of the target cell (Shneider et al. 2013). Certain Vibrionaceae adapted their antibacterial T6SS to mediate interactions with eukaryotic hosts or predators, promoting their toxicity (Dar et al. 2018).

Accession Number:Q9KN44
Protein Name:Hypothetical protein VCA0121
Length:421
Molecular Weight:48279.00
Species:Vibrio cholerae [666]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cell membrane1 / Lipid-anchor2
Substrate protein polypeptide chain, deoxyribonucleic acid

Cross database links:

RefSeq: NP_232522.1   
Entrez Gene ID: 2612830   
Pfam: PF06812   
KEGG: vch:VCA0121   

References (1)

[1] “DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.”  Heidelberg J.F.et.al.   10952301

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMSNVIFIDN VCYRLTNDSE EIRGLEPYAK VREEINRRFN PIAGGTDWAV VKEYCEQLAC 
61:	NQGMDFLICG YYAVACLKTQ GLAGYATGME LMSASLANQG ECDVKSAKVR KEILDWVNAR 
121:	VVQELKALKP TYESLRDLYR AERHCERLHQ LFEQQQTEYK VDFEGVGFAL FEHIDRIETQ 
181:	YHSLLKKQEK AQPPKLKFWQ RGYALFTLGV LGVALGMVGG YWGWPWFYTT PYAAPQRITT 
241:	LNEASQTQAL LNDSSTSERA RWQHDLIPLY RDTLQQNLTI SFSEPKRHAI TQLNLLRTLY 
301:	PENEQVNALS QEFALQQQQA LEQTALFVAK FSEIRTKMAN ISLLAKRGKW AELEKQTKSL 
361:	EEFAVSLSPI YGRVDYVQGL LEQGDVTNAQ KEFAILKQRL DSLSWKIAEL EQRIGDAALL 
421:	Q