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3.A.23.1.1
Type VI secretion system (T6SS) VasA-L + Vca0107-09; + Vca0123 + Vc1416 (Pukatzki et al., 2006; Pukatzki et al., 2007). This secretion system displays antimicrobial properties (Macintyre et al., 2010).  It functions like contractile tails of phage and penetrates cells with a trimeric VgrG spike protein to which are associated PAAR repeat proteins that sharpen the tip of the spike and are released into the cytoplasm of the target cell (Shneider et al. 2013). Certain Vibrionaceae adapted their antibacterial T6SS to mediate interactions with eukaryotic hosts or predators, promoting their toxicity (Dar et al. 2018).

Accession Number:Q9KN49
Protein Name:ClpB protein
Length:869
Molecular Weight:96230.00
Species:Vibrio cholerae [666]
Location1 / Topology2 / Orientation3: Cell membrane1 / Lipid-anchor2
Substrate protein polypeptide chain, deoxyribonucleic acid

Cross database links:

RefSeq: NP_232517.1   
Entrez Gene ID: 2612221   
Pfam: PF00004    PF07724    PF02861    PF10431   
KEGG: vch:VCA0116   

Gene Ontology

GO:0005524 F:ATP binding
GO:0017111 F:nucleoside-triphosphatase activity
GO:0005515 F:protein binding
GO:0019538 P:protein metabolic process

References (1)

[1] “DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.”  Heidelberg J.F.et.al.   10952301

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MIRIELPTLI AKLNAQSKLA LEQAASLCIE RQHPEVTLEY YLDVLLDNPL SDVRLVLKQA 
61:	GLEVDQVKQA IASTYSREQV LDTYPAFSPL LVELLQEAWL LSSTELEQAE LRSGAIFLAA 
121:	LTRADRYLSF KLISLFEGIN RENLKKHFAM ILSDSAETAV AKTDKNAANP LQAAAETPLG 
181:	RFCTNVTEQA RNGELDPVLS RENELNLMVD ILCRRRKNNP IVVGEAGVGK SAMIEGLALR 
241:	VVAGKVPTQL QNVELYSLDL GRLQAGASVK GEFEKRLKGV IDAIKQSPKP IILFIDEAHT 
301:	LIGSGNQEGG SDAANLLKPA LARGELSTVA ATTWKEYKKY FEKDPALTRR FQLVKLDEPT 
361:	IDQAVDILRG LNSVYEKAHN VLITDDALKA AAELSARYIS GRQLPDKAID VLDTACARIA 
421:	INMTTPPKRL ALLETLCHQR QLEIDMLERA QFLGQEVDSE RLDVLRNQEL ADEAEKAALT 
481:	QSWQQQKSLV ESIIALRAEL MELSQAQEQD PDHLLVVRTA LQEQYQALDA IDHAERLMHP 
541:	QVDADQIAEV IADWTGVPVD QMNTDELHKI THLTSILGQA IKGQETAIER IHRHLLTARA 
601:	DLRRPGRPKG AFLLVGPSGV GKTETVVQLA EQLYGGKQFL TTINMSEYQE KHTVSRLIGS 
661:	PPGYVGYGEG GVLTEAIRKM PYSVVLLDEV EKAHPEVLNI FYQGFDKGEI ADGEGRVIDC 
721:	QNIVFFLTSN LGYQTIVDYA DEPAKLDEAL YPELAAFFKP ALLARMEVIP YLPLGKEVLA 
781:	QIVRGKLARL EKLFKTRYNA EVVIEESLID EILSRATRSE NGARMLEAII EGQLLPPVSL 
841:	ALLNKLAERA PVERIRLAAE AGEFIGEVA