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1.A.69.2.1
The insect heteromeric CO2 receptor: GR21a (Olfactory receptor 21a; 454 aas with 7 or 8 TMSs) GR63a (Olfactory receptor 63a; 512 aas) are coexpressed in antennal neurons of insects and together comprise the peripheral sensory receptor for CO2 (Ramdya and Benton, 2010). These proteins are members of the 7Tm-7 superfamily of putative 7TMS proteins.

Accession Number:Q9VZL7
Protein Name:Gustatory and odorant receptor 63a
Length:512
Molecular Weight:57465.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate cation

Cross database links:

Pfam: PF08395   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008527 F:taste receptor activity
GO:0007610 P:behavior
GO:0003031 P:detection of carbon dioxide
GO:0050912 P:detection of chemical stimulus involved in ...
GO:0010037 P:response to carbon dioxide
GO:0007608 P:sensory perception of smell

References (5)

[1] “Two chemosensory receptors together mediate carbon dioxide detection in Drosophila.”  Jones W.D.et.al.   17167414
[2] “The genome sequence of Drosophila melanogaster.”  Adams M.D.et.al.   10731132
[3] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.”  Misra S.et.al.   12537572
[4] “A chemosensory gene family encoding candidate gustatory and olfactory receptors in Drosophila.”  Scott K.et.al.   11257221
[5] “Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.”  Dunipace L.et.al.   11516643

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MRPSGEKVVK GHGQGNSGHS LSGMANYYRR KKGDAVFLNA KPLNSANAQA YLYGVRKYSI 
61:	GLAERLDADY EAPPLDRKKS SDSTASNNPE FKPSVFYRNI DPINWFLRII GVLPIVRHGP 
121:	ARAKFEMNSA SFIYSVVFFV LLACYVGYVA NNRIHIVRSL SGPFEEAVIA YLFLVNILPI 
181:	MIIPILWYEA RKIAKLFNDW DDFEVLYYQI SGHSLPLKLR QKAVYIAIVL PILSVLSVVI 
241:	THVTMSDLNI NQVVPYCILD NLTAMLGAWW FLICEAMSIT AHLLAERFQK ALKHIGPAAM 
301:	VADYRVLWLR LSKLTRDTGN ALCYTFVFMS LYLFFIITLS IYGLMSQLSE GFGIKDIGLT 
361:	ITALWNIGLL FYICDEAHYA SVNVRTNFQK KLLMVELNWM NSDAQTEINM FLRATEMNPS 
421:	TINCGGFFDV NRTLFKGLLT TMVTYLVVLL QFQISIPTDK GDSEGANNIT VVDFVMDSLD 
481:	NDMSLMGAST LSTTTVGTTL PPPIMKLKGR KG