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1.A.1.16.6 Small conductance calcium-activated K⁺ channel, KCNN1 or SK, of 543 aas and 6 TMSs. It is a druggable risk factor for opioid use disorder (OUD) (Kember et al. 2022).
Accession Number:	Q92952
Protein Name:	Small conductance calcium-activated potassium channel protein 1
Length:	543
Molecular Weight:	59987.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	potassium(1+)

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MNSHSYNGSV GRPLGSGPGA LGRDPPDPEA GHPPQPPHSP GLQVVVAKSE PARPSPGSPR 
61:	GQPQDQDDDE DDEEDEAGRQ RASGKPSNVG HRLGHRRALF EKRKRLSDYA LIFGMFGIVV 
121:	MVTETELSWG VYTKESLYSF ALKCLISLST AILLGLVVLY HAREIQLFMV DNGADDWRIA 
181:	MTCERVFLIS LELAVCAIHP VPGHYRFTWT ARLAFTYAPS VAEADVDVLL SIPMFLRLYL 
241:	LGRVMLLHSK IFTDASSRSI GALNKITFNT RFVMKTLMTI CPGTVLLVFS ISSWIIAAWT 
301:	VRVCERYHDK QEVTSNFLGA MWLISITFLS IGYGDMVPHT YCGKGVCLLT GIMGAGCTAL 
361:	VVAVVARKLE LTKAEKHVHN FMMDTQLTKR VKNAAANVLR ETWLIYKHTR LVKKPDQARV 
421:	RKHQRKFLQA IHQAQKLRSV KIEQGKLNDQ ANTLTDLAKT QTVMYDLVSE LHAQHEELEA 
481:	RLATLESRLD ALGASLQALP GLIAQAIRPP PPPLPPRPGP GPQDQAARSS PCRWTPVAPS 
541:	DCG

1.A.1.16.6
Small conductance calcium-activated K⁺ channel, KCNN1 or SK, of 543 aas and 6 TMSs. It is a druggable risk factor for opioid use disorder (OUD) (Kember et al. 2022).

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1.A.1.16.6Small conductance calcium-activated K+ channel, KCNN1 or SK, of 543 aas and 6 TMSs. It is a druggable risk factor for opioid use disorder (OUD) (Kember et al. 2022).

Cross database links:

External Searches:

Analyze:

1.A.1.16.6
Small conductance calcium-activated K⁺ channel, KCNN1 or SK, of 543 aas and 6 TMSs. It is a druggable risk factor for opioid use disorder (OUD) (Kember et al. 2022).