TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.1.2.25
Potassium voltage-gated channel subfamily B member 2, Kv2.2 or KCNB2 of 911 aas and 6 TMSs. Selective expression of HERG (TC# 1.A.1.20.1) and Kv2 channels influences proliferation of uterine cancer cells (Suzuki and Takimoto 2004).

Accession Number:Q92953
Protein Name:Potassium voltage-gated channel subfamily B member 2
Length:911
Molecular Weight:102563.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate potassium(1+)

Cross database links:

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MAEKAPPGLN RKTSRSTLSL PPEPVDIIRS KTCSRRVKIN VGGLNHEVLW RTLDRLPRTR 
61:	LGKLRDCNTH ESLLEVCDDY NLNENEYFFD RHPGAFTSIL NFYRTGKLHM MEEMCALSFG 
121:	QELDYWGIDE IYLESCCQAR YHQKKEQMNE ELRREAETMR EREGEEFDNT CCPDKRKKLW 
181:	DLLEKPNSSV AAKILAIVSI LFIVLSTIAL SLNTLPELQE TDEFGQLNDN RQLAHVEAVC 
241:	IAWFTMEYLL RFLSSPNKWK FFKGPLNVID LLAILPYYVT IFLTESNKSV LQFQNVRRVV 
301:	QIFRIMRILR ILKLARHSTG LQSLGFTLRR SYNELGLLIL FLAMGIMIFS SLVFFAEKDE 
361:	DATKFTSIPA SFWWATITMT TVGYGDIYPK TLLGKIVGGL CCIAGVLVIA LPIPIIVNNF 
421:	SEFYKEQKRQ EKAIKRREAL ERAKRNGSIV SMNLKDAFAR SMELIDVAVE KAGESANTKD 
481:	SADDNHLSPS RWKWARKALS ETSSNKSFEN KYQEVSQKDS HEQLNNTSSS SPQHLSAQKL 
541:	EMLYNEITKT QPHSHPNPDC QEKPERPSAY EEEIEMEEVV CPQEQLAVAQ TEVIVDMKST 
601:	SSIDSFTSCA TDFTETERSP LPPPSASHLQ MKFPTDLPGT EEHQRARGPP FLTLSREKGP 
661:	AARDGTLEYA PVDITVNLDA SGSQCGLHSP LQSDNATDSP KSSLKGSNPL KSRSLKVNFK 
721:	ENRGSAPQTP PSTARPLPVT TADFSLTTPQ HISTILLEET PSQGDRPLLG TEVSAPCQGP 
781:	SKGLSPRFPK QKLFPFSSRE RRSFTEIDTG DDEDFLELPG AREEKQVDSS PNCFADKPSD 
841:	GRDPLREEGS VGSSSPQDTG HNCRQDIYHA VSEVKKDSSQ EGCKMENHLF APEIHSNPGD 
901:	TGYCPTRETS M