1.A.1.2.25 Potassium voltage-gated channel subfamily B member 2, Kv2.2 or KCNB2 of 911 aas and 6 TMSs. Selective expression of HERG (TC# 1.A.1.20.1) and Kv2 channels influences proliferation of uterine cancer cells (Suzuki and Takimoto 2004).
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Accession Number: | Q92953 |
Protein Name: | Potassium voltage-gated channel subfamily B member 2 |
Length: | 911 |
Molecular Weight: | 102563.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 7 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
potassium(1+) |
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1: MAEKAPPGLN RKTSRSTLSL PPEPVDIIRS KTCSRRVKIN VGGLNHEVLW RTLDRLPRTR
61: LGKLRDCNTH ESLLEVCDDY NLNENEYFFD RHPGAFTSIL NFYRTGKLHM MEEMCALSFG
121: QELDYWGIDE IYLESCCQAR YHQKKEQMNE ELRREAETMR EREGEEFDNT CCPDKRKKLW
181: DLLEKPNSSV AAKILAIVSI LFIVLSTIAL SLNTLPELQE TDEFGQLNDN RQLAHVEAVC
241: IAWFTMEYLL RFLSSPNKWK FFKGPLNVID LLAILPYYVT IFLTESNKSV LQFQNVRRVV
301: QIFRIMRILR ILKLARHSTG LQSLGFTLRR SYNELGLLIL FLAMGIMIFS SLVFFAEKDE
361: DATKFTSIPA SFWWATITMT TVGYGDIYPK TLLGKIVGGL CCIAGVLVIA LPIPIIVNNF
421: SEFYKEQKRQ EKAIKRREAL ERAKRNGSIV SMNLKDAFAR SMELIDVAVE KAGESANTKD
481: SADDNHLSPS RWKWARKALS ETSSNKSFEN KYQEVSQKDS HEQLNNTSSS SPQHLSAQKL
541: EMLYNEITKT QPHSHPNPDC QEKPERPSAY EEEIEMEEVV CPQEQLAVAQ TEVIVDMKST
601: SSIDSFTSCA TDFTETERSP LPPPSASHLQ MKFPTDLPGT EEHQRARGPP FLTLSREKGP
661: AARDGTLEYA PVDITVNLDA SGSQCGLHSP LQSDNATDSP KSSLKGSNPL KSRSLKVNFK
721: ENRGSAPQTP PSTARPLPVT TADFSLTTPQ HISTILLEET PSQGDRPLLG TEVSAPCQGP
781: SKGLSPRFPK QKLFPFSSRE RRSFTEIDTG DDEDFLELPG AREEKQVDSS PNCFADKPSD
841: GRDPLREEGS VGSSSPQDTG HNCRQDIYHA VSEVKKDSSQ EGCKMENHLF APEIHSNPGD
901: TGYCPTRETS M