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1.A.105.1.1 The mixed lineage kinase domain-like (MLKL) protein of 471 aas and 5 TMSs; forms Mg²⁺-selective channels in the presence of Na⁺ and K⁺ (Xia et al. 2016).
Accession Number:	Q8NB16
Protein Name:	Mixed lineage kinase domain-like protein
Length:	471
Molecular Weight:	54479.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Cytoplasm¹
Substrate	magnesium(2+)

Structure:
2MSV 4M67 4MWI 5KNJ 5KO1 6BWK 6D74 6O5Z 6UX8 [...more]

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MENLKHIITL GQVIHKRCEE MKYCKKQCRR LGHRVLGLIK PLEMLQDQGK RSVPSEKLTT 
61:	AMNRFKAALE EANGEIEKFS NRSNICRFLT ASQDKILFKD VNRKLSDVWK ELSLLLQVEQ 
121:	RMPVSPISQG ASWAQEDQQD ADEDRRAFQM LRRDNEKIEA SLRRLEINMK EIKETLRQYL 
181:	PPKCMQEIPQ EQIKEIKKEQ LSGSPWILLR ENEVSTLYKG EYHRAPVAIK VFKKLQAGSI 
241:	AIVRQTFNKE IKTMKKFESP NILRIFGICI DETVTPPQFS IVMEYCELGT LRELLDREKD 
301:	LTLGKRMVLV LGAARGLYRL HHSEAPELHG KIRSSNFLVT QGYQVKLAGF ELRKTQTSMS 
361:	LGTTREKTDR VKSTAYLSPQ ELEDVFYQYD VKSEIYSFGI VLWEIATGDI PFQGCNSEKI 
421:	RKLVAVKRQQ EPLGEDCPSE LREIIDECRA HDPSVRPSVD EILKKLSTFS K

1.A.105.1.1
The mixed lineage kinase domain-like (MLKL) protein of 471 aas and 5 TMSs; forms Mg²⁺-selective channels in the presence of Na⁺ and K⁺ (Xia et al. 2016).

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1.A.105.1.1The mixed lineage kinase domain-like (MLKL) protein of 471 aas and 5 TMSs; forms Mg2+-selective channels in the presence of Na+ and K+ (Xia et al. 2016).

Cross database links:

External Searches:

Analyze:

1.A.105.1.1
The mixed lineage kinase domain-like (MLKL) protein of 471 aas and 5 TMSs; forms Mg²⁺-selective channels in the presence of Na⁺ and K⁺ (Xia et al. 2016).