TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.108.1.1
Fibroblast growth factor 2, FGF2, of 288 aas.  Forms oligomeric pores in the plasma membrane, and these are involved in its secretion to the external medium where it exerts its action (La Venuta et al. 2016; see family description). The ATP1A1 (TC# 3.A.3.1.1) serves as the receptor for membrane insertion (Zacherl et al. 2015).

Accession Number:P09038
Protein Name:Fibroblast growth factor 2
Length:288
Molecular Weight:30770.00
Species:Homo sapiens (Human) [9606]
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules, FGF2

Cross database links:

Structure:
1BAS   1BFB   1BFC   1BFF   1BFG   1BLA   1BLD   1CVS   1EV2   1FGA   [...more]

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MVGVGGGDVE DVTPRPGGCQ ISGRGARGCN GIPGAAAWEA ALPRRRPRRH PSVNPRSRAA 
61:	GSPRTRGRRT EERPSGSRLG DRGRGRALPG GRLGGRGRGR APERVGGRGR GRGTAAPRAA 
121:	PAARGSRPGP AGTMAAGSIT TLPALPEDGG SGAFPPGHFK DPKRLYCKNG GFFLRIHPDG 
181:	RVDGVREKSD PHIKLQLQAE ERGVVSIKGV CANRYLAMKE DGRLLASKCV TDECFFFERL 
241:	ESNNYNTYRS RKYTSWYVAL KRTGQYKLGS KTGPGQKAIL FLPMSAKS