1.A.110.1.10
Otop3 of 600 aas and 12 TMSs in a 5 + 5 + 2 TMS arrangement. The high resolution 3-d structure has been determined by cryoEM (Saotome et al. 2019) (see family description). Applications of solution NMR for studying structure, dynamics, and interactions of polytopic integral membrane proteins have been reviewed (Danmaliki and Hwang 2020).
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| Accession Number: | R4GK65 |
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| Protein Name: | Uncharacterized protein |
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| Length: | 600 |
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| Molecular Weight: | 67643.00 |
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| Species: | Gallus gallus (Chicken) [9031] |
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| Number of TMSs: | 12 |
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| Substrate |
hydron |
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1: MAGNKASKQK FCHHCNSRSA SAPPGTSTIH YEKSWLYRHC SLQQRDRQAQ KSGQLFSGLL
61: ALNVVFLGSA FISSMIFNHV AITLADVWIL LSILKVLCLC WIIYYLLGTS RQPHAVLYRD
121: THAGPVWIRG SLLLFGTFSI LLNVFQIGYS VIQINCKSKV EIVFPSIEIL FVATQAFFLW
181: HHSKDCIQVQ HNLTRCGLML TIATNLLLWL LAVTNDSIHM EIESQLREVE QRLAGNETDS
241: CACPNTTTCK VFQKGYILLY PFNTEYCLIC CSVLYVMWKN VGRRISHHHI AHIKPKFKLQ
301: GVVFGPLLGA AAVIIGICVF MMYQIQATGS APNYQVFVLY YSYYIVLLPL MCVVAIIGTI
361: IHTLEKRELD TLKNPTRSLD VVLLMGAALG QIAMSYFSIV AIVATNPRDM LNSLILSYSV
421: LLIFQYITQN IFIIDGLQRQ PFAAAEAQHT THAGQLSAVP ELPGEGVTTP SSNQERSQTF
481: PSKEEEVSEE HNREAPDQRR VSVLELGQEF RRVSLSYIHT YSHLGWKRKA LKEISFFLVL
541: CNIILWIMPT FGAHPVFENG LQKSFYGYST WFAIVNFGLP LSVFYRMHSV GGLLEVYVSA