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1.A.110.1.2 OTOP1 H⁺ channel of 612 aas and 10 TMSs (Tu et al. 2018). OTOP1 is a protein required for development of gravity-sensing otoconia in the vestibular system. It forms a proton-selective ion channel (Tu et al. 2018).
Accession Number:	Q7RTM1
Protein Name:	Otopetrin-1
Length:	612
Molecular Weight:	67353.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	10
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	hydron, proton

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MLEGLGSPAS PRAAASASVA GSSGPAACSP PSSSAPRSPE SPAPRRGGVR ASVPQKLAEM 
61:	LSSQYGLIVF VAGLLLLLAW AVHAAGVSKS DLLCFLTALM LLQLLWMLWY VGRSSAHRRL 
121:	FRLKDTHAGA GWLRGSITLF AVITVILGCL KIGYFIGFSE CLSATEGVFP VTHSVHTLLQ 
181:	VYFLWGHAKD IIQSFKTLER FGVIHSVFTN LLLWANGVLN ESKHQLNEHK ERLITLGFGN 
241:	ITTVLDDHTP QCNCTPPTLC TAISHGIYYL YPFNIEYQIL ASTMLYVLWK NIGRKVDSHQ 
301:	HQKMQFKSDG VMVGAVLGLT VLAATIAVVV VYLIHIGRSK TKSESALIMF YLYAITLLML 
361:	MGAAGLAGIR IYRIDEKSLD ESKNPARKLD SDLLVGTASG SWLISWGSIL AILCAEGHPR 
421:	YTWYNLPYSI LAIVEKYIQN LFIFESIHRE PEKLSEDIQT LRVVTVCNGN TMPLASSCPK 
481:	SGGVARDVAP QGKDMPPAAN GNVCMRESHD KEEEKQEESS WGGSPSPVRL PRFLQGNAKR 
541:	KVLRNIAAFL FLCNISLWIP PAFGCRPEYD NGLEEIVFGF EPWIIVVNLA MPFSIFYRMH 
601:	AAASLFEVYC KI

1.A.110.1.2
OTOP1 H⁺ channel of 612 aas and 10 TMSs (Tu et al. 2018). OTOP1 is a protein required for development of gravity-sensing otoconia in the vestibular system. It forms a proton-selective ion channel (Tu et al. 2018).

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1.A.110.1.2OTOP1 H+ channel of 612 aas and 10 TMSs (Tu et al. 2018). OTOP1 is a protein required for development of gravity-sensing otoconia in the vestibular system. It forms a proton-selective ion channel (Tu et al. 2018).

Cross database links:

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1.A.110.1.2
OTOP1 H⁺ channel of 612 aas and 10 TMSs (Tu et al. 2018). OTOP1 is a protein required for development of gravity-sensing otoconia in the vestibular system. It forms a proton-selective ion channel (Tu et al. 2018).