1.A.110.1.3
OTOP2 H+ channel of 562 aas and 10 TMSs in a 5 + 5 + 2 arrangement (Tu et al. 2018).
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| Accession Number: | Q7RTS6 |
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| Protein Name: | Otopetrin-2 |
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| Length: | 562 |
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| Molecular Weight: | 62236.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 12 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
hydron |
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1: MSEELAQGPK ESPPAPRAGP REVWKKGGRL LSVLLAVNVL LLACTLISGG AFNKVAVYDT
61: DVFALLTAMM LLATLWILFY LLRTVRCPCA VPYRDAHAGP IWLRGGLVLF GICTLIMDVF
121: KTGYYSSFFE CQSAIKILHP LIQAVFVIIQ TYFLWVSAKD CVHVHLDLTW CGLMFTLTTN
181: LAIWMAAVVD ESVHQSHSYS SSHSNASHAR LISDQHADNP VGGDSCLCST AVCQIFQQGY
241: FYLYPFNIEY SLFASTMLYV MWKNVGRFLA STPGHSHTPT PVSLFRETFF AGPVLGLLLF
301: VVGLAVFIIY EVQVSGDGSR TRQALVIYYS FNIVCLGLTT LVSLSGSIIY RFDRRAMDHH
361: KNPTRTLDVA LLMGAALGQY AISYYSIVAV VAGTPQDLLA GLNLTHALLM IAQHTFQNMF
421: IIESLHRGPP GAEPHSTHPK EPCQDLTFTN LDALHTLSAC PPNPGLVSPS PSDQREAVAI
481: VSTPRSQWRR QCLKDISLFL LLCNVILWIM PAFGARPHFS NTVEVDFYGY SLWAVIVNIC
541: LPFGIFYRMH AVSSLLEVYV LS