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1.A.110.1.9
The OTOP3 protopn channel protein of 681 aas and 12 TMSs. The cryo-EM structure along with functional characteristics have been described (Chen et al. 2019). XtOTOP3 forms a homodimer with each subunit containing 12 transmembrane helices that can be divided into two structurally homologous halves; each half assembles as an alpha-helical barrel that could serve as a proton conduction pore.

Accession Number:A9JTM7
Protein Name:LOC100127796 protein
Length:681
Molecular Weight:76724.00
Species:Xenopus tropicalis (Western clawed frog) [8364]
Number of TMSs:12
Substrate

Cross database links:

Structure:
6O84     

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLSKEEPACR QFHSREKTWG NEHNGKTVTQ ANNKEHKVPA VRRGDIGQRE PAAHPASHIQ 
61:	GTMASENTGE QATCKDQYMD LDAPGNNLEH SWLHRHCEIP TTLHQRAKKT GRLFSGLFGL 
121:	NLMFLGGTVV SSVALSNKAV PERDSQSFLC ILMLLSSVWA LYHLLFIRNQ NGAVHHDHHA 
181:	GAMWLKASLA IFGVCSIILS IFEIGHALLL QNCEILMDIV FFSIEIVFVS VQTVLLWVSC 
241:	KDCVQMHHSV TRYGIMLTLA TDILLWLTAV IDDSLEQDLE ILQSNSTQDE SNEMAQCQCP 
301:	TDSMCWGLKQ GYVTMFPFNI EYSLICATLL FIMWKNVGRR EKLHSDPPRH TFQLRGIIYG 
361:	PLIGGAALLV GISVFVQYQV EATSGMVSIL SYHMYYGYKM IILAPMIVCS VAGIIAHSLR 
421:	EKEKKGQKET GRSDQDWLHM EDVGSENKNT DYSSGQYQSS QGDEKIQGYS LAQFALDNEK 
481:	EKLEHRQGNT TKKHNTHQGK MKNYTRKLDV TLLFVSAVGQ LGISYFSIIA TVVTTPWTML 
541:	SALNFSNSLL LILQYLSQTM FIIESMRSIH EEEKEKPGHH EESHRRMSVQ EMHKAPPSCL 
601:	DAGHLGLSRR VVKEMAMFLM ICNIMCWILG AFGAHPLYMN GLERQLYGSG IWLAILNIGL 
661:	PLSVFYRMHS VGILLEVYLH A