1.A.112.2.10
Magnesium and cobalt efflux protein, CorC or MpfA (Magnesium Protection Factor A) of 449 aas and 4 N-terminal TMSs, apparently in a 2 + 2 TMS arrangement. Evidence has been presented that this protein catalyzes active Mg2+ extrusion from the cell (Armitano et al. 2016). If so, It must be an active transporter, either a secondary carrier (TC subclass 2.A) or an ATP hydrolysis-driven exporter (TC subclass 3.A).
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| Accession Number: | T1Y8N2 |
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| Protein Name: | Magnesium and cobalt efflux protein corC |
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| Length: | 449 |
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| Molecular Weight: | 51150.00 |
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| Species: | Staphylococcus aureus subsp. aureus CN1 [1193576] |
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| Number of TMSs: | 4 |
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| Substrate |
magnesium(2+) |
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1: METSTIISLI IFILLIALTT VFVGSEFALV KIRATRIEQL ADEGNKPAKI VKKMIANLDY
61: YLSACQLGIT VTSLGLGWLG EPTFEKLLHP IFEAINLPTA LTTTISFAVS FIIVTYLHVV
121: LGELAPKSIA IQHTEKLALV YARPLFYFGN IMKPLIWLMN GSARVIIRMF GVNPDAQTDA
181: MSEEEIKIII NNSYNGGEIN QTELAYMQNI FSFDERHAKD IMVPRTQMIT LNEPFNVDEL
241: LETIKEHQFT RYPITDDGDK DHIKGFINVK EFLTEYASGK TIKIANYIHE LPMISETTRI
301: SDALIRMQRE HVHMSLIIDE YGGTAGILTM EDILEEIVGE IRDEFDDDEV NDIVKIDNKT
361: FQVNGRVLLD DLTEEFGIEF DDSEDIDTIG GWLQSRNTNL QKDDYVDTTY DRWVVSEIDN
421: HQIIWVILNY EFNEARPTIG QSDEDEKSE