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1.A.112.2.2
Uncharacterized protein of 434 aas with an N-terminal 4 TMSs, YrkA.

Accession Number:P54428
Protein Name:YrkA
Length:434
Molecular Weight:48985.00
Species:Bacillus subtilis [1423]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

HEGENOM: HBG673071
RefSeq: NP_390538.1   
Entrez Gene ID: 937634   
Pfam: PF00571    PF03471    PF01595   
KEGG: bsu:BSU26610   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (4)

[1] “Sequence of the Bacillus subtilis genome region in the vicinity of the lev operon reveals two new extracytoplasmic function RNA polymerase sigma factors SigV and SigZ.”  Sorokin A.et.al.   9308178
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[3] “Systematic sequencing of the 283 kb 210 degrees-232 degrees region of the Bacillus subtilis genome containing the skin element and many sporulation genes.”  Mizuno M.et.al.   8969508
[4] “Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated.”  Ahmed M.et.al.   7608059

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTTINLIIFT LLIVLTAFFV ATEFAIVKIR SSKIDQLILE GKKGAISAKK VITHLDEYLS 
61:	ACQLGITVTA LGIGWVGEST FEVILHPLFA HFHVSETVSH VLILVIAFVM ATFLHVVVGE 
121:	LAPKTLAIQK AETITLLTAK PIIWFYRILF PFIWFLNGSA RFIVGLFGLK PASEHELAHS 
181:	EEELRILLSE SYKSGEINQN ELKYVNNIFE FDERIAKEIM IPRREIVAIS SEDSYETIVK 
241:	IIKTESYTRY PVLNGDKDSI IGFINAKEFL SAYIDTDQKI KEDFKLENHI NPVIHVIESV 
301:	PIHDVLVKMQ KERTHIAILV DEYGGTSGLV TAEDILEEIV GEIRDEFDKD EVPNIRKVND 
361:	NHYILDSKVL IEDVNDLLGT TLASDEVDTI GGWFMTQQID AAVGSVIEAD GYIFKVHETV 
421:	GRHINYLEIV RKKE