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1.A.114.1.2 Proton-activated chloride channel of 298 aas and 2 TMSs. It mediates import of chloride ion in response to extracellular acidic pH (Yang et al. 2019) and displays channel activity with kinetic properties distinct from that of the human ortholog.
Accession Number:	Q7SY31
Protein Name:	Proton-activated chloride channel
Length:	298
Molecular Weight:	34687.00
Species:	Danio rerio (Zebrafish) [7955]
Number of TMSs:	2
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	anion, chloride

UniProt (Universal Protein Resource)
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FASTA formatted sequence

1:	MPIGFNKACL KNVFTVILVL IYLALTAVAV FLAYQTISDF MDKLNHPVMS VSYKEVEEFA 
61:	APGIVLFPGK AHLLSCMHHY HDNIPPLVAL ENLAKRECMK EEVIYHGPYS NQTEKRALVF 
121:	RGPTDVRNRE LIFLQLSRNE TEEDFSAISY MIFAKFSDML ESSDKAAFMM DCERNYSMWT 
181:	FSGGFRTWVK MSLVRTSGRR NESVEFRQES SVVKYIDKRP PLEQTNELFF IVFQWRDPFI 
241:	QQVKDIVTAN PWNTIAILCG VFMALFKAAD FAKLSIKWMI RIRKRHIRAK MREMNQIS

1.A.114.1.2
Proton-activated chloride channel of 298 aas and 2 TMSs. It mediates import of chloride ion in response to extracellular acidic pH (Yang et al. 2019) and displays channel activity with kinetic properties distinct from that of the human ortholog.

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1.A.114.1.2Proton-activated chloride channel of 298 aas and 2 TMSs. It mediates import of chloride ion in response to extracellular acidic pH (Yang et al. 2019) and displays channel activity with kinetic properties distinct from that of the human ortholog.

Cross database links:

External Searches:

Analyze:

1.A.114.1.2
Proton-activated chloride channel of 298 aas and 2 TMSs. It mediates import of chloride ion in response to extracellular acidic pH (Yang et al. 2019) and displays channel activity with kinetic properties distinct from that of the human ortholog.