TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.A.119.1.1









The drought stress-inducible putative membrane protein, TMPIT1

Eukaryota
Viridiplantae
TMPIT1 of Triticum dicoccoides (G0ZL54)
1.A.119.1.2









The TMEM120A or TACAN protein , of 343 aas and 7 TMSs.  May function in adipogenesis (Batrakou et al. 2015). TACAN is a Ca2+-transporting ion channel involved in sensing mechanical pain. It is expressed in a subset of nociceptors in humans, and its heterologous expression increases mechanically evoked currents in cell lines. Purification and reconstitution of TACAN in synthetic lipids generates a functional ion channel that transports Ca2+ (Beaulieu-Laroche et al. 2020).

Eukaryota
Metazoa
TACAN of Homo sapiens
1.A.119.1.3









TACAN-like protein (homologue) of 199 aas and 7 TMSs

Eukaryota
Metazoa
TACAN of Arabidopsis thaliana (thale cress)
1.A.119.1.4









Uncharacterized protein of 113 aas and 2 TMSs. This protein corresponds to the last two TMSs in 1.A.119.1.2.  It could be a short version of the latter protein, or it could be an incomplete sequence.

Eukaryota
Metazoa
UP of Schistosoma curassoni
1.A.119.1.5









Uncharacterized protein of 105 aas and 2 TMSs. This protein corresponds to the last two TMSs of the protein listed under TC# 1.A.119.1.2.  It could be a short version of the latter protein, or it could be an incomplete sequence.

Eukaryota
Metazoa
UP of Dibothriocephalus latus
1.A.119.1.6









Uncharacterized protein of 131 aas and 2 TMSs. This protein corresponds to the last two TMSs of the protein with TC# 1.A.119.1.2.  It could be a short version of the latter protein, or it could be an incomplete sequence. However, there seem to be multiple versions of this short protein (see TC#s 1.A.119.1.4, 1.5, and 1.6) suggesting that it may be a full-length protein. Also, the two N-terminal TMSs are followed in this protein by a hydrophilic region not present in the other homologues.

Eukaryota
Metazoa
UP of Nippostrongylus brasiliensis
1.A.119.1.7









Uncharacterized protein of 268 aas with two C-terminal TMSs and a long hydrophilic N-terminal domain. The C-terminus is very similar to that of TC# 1.A.119 .1.5.

Eukaryota
Metazoa
UP of Schistocephalus solidus
1.A.119.1.8









TMPIT-like protein of 355 aas and 7 TMSs

Eukaryota
Viridiplantae
TMPIT protein of Dunaliella salina
1.A.119.1.9









Transmembrane 120-like protein of 747 aas and 8 probable TMSs in the central part of the protein.

Eukaryota
Viridiplantae
TMEM120 of Chlorella sorokiniana
1.A.119.1.10









Uncharacterized protein of 124 aas and 2 TMSs. This could be a fragment.

Archaea
UP of an archaeon (phyllosphere metagenome)
1.A.119.1.11









Uncharacterized protein of 409 aas and 7 TMSs.

Eukaryota
Viridiplantae
UP of Chlorella variabilis
1.A.119.1.12









Uncharacterized protein of 325 aas and 5 TMSs in a 2 + 1 + 2 TMS arrangement.

Eukaryota
Rhizaria
UP of Reticulomyxa filosa