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1.A.12.1.3 Organellar chloride channel, CLIC-5A (251 aas; 2 TMSs; one of six homologous human genes) (95% identical to 1.A.12.1.1 but lacks the N-terminal 185 residues.) It associates with the cortical actin cytoskeleton (Berryman et al., 2004).
Accession Number:	Q53G01
Protein Name:	Chloride intracellular channel 5 variant
Length:	251
Molecular Weight:	28179.00
Species:	Homo sapiens (Human) [9606]
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	chloride

RefSeq:	NP_001107558.1 NP_058625.2
Entrez Gene ID:	53405
KEGG:	hsa:53405
Gene Ontology GO:0016020 C:membrane GO:0005247 F:voltage-gated chloride channel activity GO:0006821 P:chloride transport
References (2) [1] “Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.” Maruyama K.et.al. 8125298 [2] “Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.” Suzuki Y.et.al. 9373149

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MTDSATANGD DRDPEIELFV KAGIDGESIG NCPFSQRLFM ILWLKGVVFN VTTVDLKRKP 
61:	ADLHNLAPGT HPPFLTFNGD VKTDVNKIEE FLEETLTPEK YPKLAAKHRE SNTAGIDIFS 
121:	KFSAYIKNTK QQNNAALERG LTKALKKLDD YLNTPLPEEI DANTCGEDKG SRRKFLDGDE 
181:	LTLADCNLLP KLHVVKIVAK KYRNYDIPAE MTGLWRYLKN AYARDEFTNT CAADSEIELA 
241:	YADVAKRLSR S

1.A.12.1.3
Organellar chloride channel, CLIC-5A (251 aas; 2 TMSs; one of six homologous human genes) (95% identical to 1.A.12.1.1 but lacks the N-terminal 185 residues.) It associates with the cortical actin cytoskeleton (Berryman et al., 2004).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

1.A.12.1.3Organellar chloride channel, CLIC-5A (251 aas; 2 TMSs; one of six homologous human genes) (95% identical to 1.A.12.1.1 but lacks the N-terminal 185 residues.) It associates with the cortical actin cytoskeleton (Berryman et al., 2004).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

1.A.12.1.3
Organellar chloride channel, CLIC-5A (251 aas; 2 TMSs; one of six homologous human genes) (95% identical to 1.A.12.1.1 but lacks the N-terminal 185 residues.) It associates with the cortical actin cytoskeleton (Berryman et al., 2004).