1.A.120.1.3
ORF1a polyprotein, partial of 4345 aas and ~ 7 TMSs. A cell-based system combined with flow cytometry has been used to evaluate
antibody responses against SARS-CoV-2 transmembrane proteins in
patients with COVID-19 (Martin et al. 2022).
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| Accession Number: | QMU93623 |
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| Protein Name: | QMU93623.1 ORF1a polyprotein, partial [Severe acute respiratory syndrome coronavirus 2] |
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| Length: | 4346 |
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| Molecular Weight: | |
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| Species: | Severe acute respiratory syndrome coronavirus 2 [2697049] |
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| Number of TMSs: | 8 |
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| Substrate |
(ribonucleotide)n+m |
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1: LVRGFGDSVE EVLSEARQHL KDGTCGLVEV EKGVLPQLEQ PYVFIKRSDA RTAPHGHVMV
61: ELVAELEGIQ YGRSGETLGV LVPHVGEIPV AYRKVLLRKN GNKGAGGHSY GADLKSFDLG
121: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
181: XXXXXXXXXX XXXXXXXXXX XXXXXXXXEH EIAWYTERSE KSYELQTPFE IKLAKKFDTF
241: NGECPNFVFP LNSIIKTIQP RVEKKKLDGF MGRIRSVYPV ASPNECNQMC LSTLMKCDHC
301: GETSWQTGDF VKATCEFCGT ENLXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
361: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXGL
421: NDNLLEILQK EKVNINIVGD FKLNEEIAII LASFSASTSA FVETVKGLDY KAFKQIVESC
481: GNFKVTKGKA KKGAWNIGEQ KSILSPLYAF ASEAARVVRS IFSRTLETAQ NSVXXXXXXX
541: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
601: XXXXXXXXXX XXXXXXXXXX XIVKFISTCA CEIVGGQIVT CAKEIKESVQ TFFKLVNKFL
661: ALCADSIIIG GAKLKALNLG ETFVTHSKGL YRKCVKSREE TGLLMPLKAP KEIIFLEGET
721: LPTEVLTEEV VLKTGDLQPL EXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
781: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXELGT
841: EVNEFACVVA DAVIKTLQPV SELLTPLGID LDEWSMATYY LFDESGEFKL ASHMYCSFYP
901: PDEDEEEGDC EEEEFEPSTQ YEYGTEDDYQ GKPLEFGATS AALQPEEEQE EDWLDDDSQQ
961: TVGQQDGSED NQTTTIQTIV EVQPQLEMEL TPVVQTIEVN SFSGYLKLTD NVYIKNADIV
1021: EEAKKVKPTV VVNAANVYLK HGGGVAGALN KATNNAMQVE SDDYIATNGP LKVGGSCVLS
1081: GHNLAKHCLH VVGPNVNKGE DIQLLKSAYE NFNQHEVLLA PLLSAGIFGA DPIHSLRVCV
1141: DTVRTNVYLA VFDKNLYDKL VXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
1201: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXSDIDI TFLKKDAPYI
1261: VGDVVQEGVL TAVVIPTKKA GGTTEMLAKA LRKVPTDNYI TTYPGQGLNG YTVEEAKTVL
1321: KKCKSAFYIL PSIISNEKQE ILGTVSWNLR EMLAHAEETR KXXXXXXXXX XXXXXXXXXX
1381: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXM
1441: RSLKVPATVS VSSPDAVTAY NGYLTSSSKT PEEHFIETIS LAGSYKDWSY SGQSTQLGIE
1501: FLKRGDKSVY YTSNPTTFHL DGEVITFDNL KTLLSLREVR TIKVFTTVDN XXXXXXXXXX
1561: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
1621: XXXXXXXXXX XXXXXXXXXX XXXXXXXXYL ATALLTLQQI ELKFNPPALQ DAYYRARAGE
1681: AANFCALILA YCNKTVGELG DVRETMSYLF QHANLDSCKR VLNVVCKTCG QQQTTLKGVE
1741: AVMYMGTLSY EQFKKGVQIX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
1801: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XKPVTYKLDG
1861: VVCTEIDPKL DNYYKKDNSY FTEQPIDLVP NQPYPNASFD NFKFVCDNIK FADDLNQLTG
1921: YKKPASRELK VTFFPDLNGD VVAIDYKHYT PSFKKGAKLL HKPIVWHVXX XXXXXXXXXX
1981: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
2041: XXXXXXXXXX XKPANNSLKI TEEVGHTDLM AAYVDNSSLT IKKPNELSRV LGLKTLATHG
2101: LAAVNSVPWD TIANYAKPFL NKVVSTTTNI VTRCLNRVCT NYMPYFFTLL LQLCTFTRST
2161: NSRIKASXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
2221: XXXXXXXXXX XXXXXXXXXY REGYLNSTNV TIATYCTGSI PCSVCLSGLD SLDTYPSLET
2281: IQITISSFKW DLTAFGLVAE WFLAYILFTR FFYVLGLAAI MQLFFSYFAV HFISNSWLMW
2341: LIINLVQMAX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
2401: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXTFIS DEVARDLSLQ FKRPINPTDQ
2461: SSYIVDSVTV KNGSIHLYFD KAGQKTYERH SLSHFVNLDN LRANNTKGSL PINVIVFDGK
2521: SKCEESSAKS ASVYYSQLMC QPILLLDQAL VXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
2581: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
2641: XXXXNNYMLT YNKVENMTPR DLGACIDCSA RHINAQVAKS HNIALIWNVK DFMSLSEQLR
2701: KQIRSAAKKN NLPFKLTCAT TRQVVNVVTT KIALKGGKIV NNWLKQLIKV TLVFLFVAAI
2761: FYLIXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
2821: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXFLP RVFSAVGNIC YTPSKLIEYT
2881: DFATSACVLA AECTIFKDAS GKPVPYCYDT NVLEGSVAYE SLRPDTRYVL MDGSIIQFPN
2941: TYLEGSVRVV TTFDSEYCRH GTCERSEXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
3001: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXFNTLLFL
3061: MSFTVLCLTP VYSFLPGVYS VIYLYLTFYL TNDVSFLAHI QWMVMFTPLV PFWITIAYII
3121: CISTKHFYWF FSNYLKRRVV FNGVSFSTFE EAALCTFLLN KEMXXXXXXX XXXXXXXXXX
3181: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
3241: XXXXXXXXXX XXCMVQVTCG TTTLNGLWLD DVVYCPRHVI CTSEDMLNPN YEDLLIRKSN
3301: HNFLVQAGNV QLRVIGHSMQ NCVLKLKVDT ANPKTPKYKF VRIQPGQTFS VLACYNGSPS
3361: GVYQXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
3421: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXI NGDRWFLNRF TTTLNDFNLV AMKYNYEPLT
3481: QDHVDILGPL FAQTGIAVLD MCASLKELLQ NGMNGRTILG SALLEDEFTP FDVVRQCSGV
3541: TFQSAVKRTI KGTHHWLLLT ILTSLLVLXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
3601: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
3661: XXXVLLILMT ARTVYDDGAR RVWTLMNVLT LVYKVYYGNA LDQAISMWAL IISVTSNYSG
3721: VVTTVMFLAR GIVFMCVEYC PIFFITGNTL QCIMLVYCFL GYFCTCYFGL FCLLNXXXXX
3781: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
3841: XXXXXXXXXL QQLRVESSSK LWAQCVQLHN DILLAKDTTE AFEKMVSLLS VLLSMQGAVD
3901: INKLCEEMLD NRATLQAIAS EFSSLPSYAA FATAQEAYEQ AVANGDSEVV LKKLKKSLNV
3961: AKSXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
4021: XXXXXXXXXX XXLNIIPLTT AAKLMVVIPD YNTYKNTCDG TTFTYASALW EIQQVVDADS
4081: KIVQLSEISM DNSPNLAWPL IVTALRANSA VKLQNNELSP VALRQMSCAA GTTQTACTDD
4141: NALAYXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
4201: XXXXXXXXXX XXXXXXXXXX XXXXXXXXXN ATEVPANSTV LSFCAFAVDA AKAYKDYLAS
4261: GGQPITNCVK MLCTHTGTGQ AITVTPEANM DQESFGGASC CLYCRCHIDH PNPKGFCDLK
4321: GKYVQIPTTC ANDPVGFTLK NTVCT