1.A.121.1.1 Anterior pharynx-defective 2 (APH-1B) water channel protein of 257 aas and 7 TMSs in a 3 + 1 + 3 TMS arrangement (Dehury and Kepp 2020).
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Accession Number: | Q8WW43 |
Protein Name: | Gamma-secretase subunit APH-1B |
Length: | 257 |
Molecular Weight: | 28460.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 7 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
water |
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1: MTAAVFFGCA FIAFGPALAL YVFTIATEPL RIIFLIAGAF FWLVSLLISS LVWFMARVII
61: DNKDGPTQKY LLIFGAFVSV YIQEMFRFAY YKLLKKASEG LKSINPGETA PSMRLLAYVS
121: GLGFGIMSGV FSFVNTLSDS LGPGTVGIHG DSPQFFLYSA FMTLVIILLH VFWGIVFFDG
181: CEKKKWGILL IVLLTHLLVS AQTFISSYYG INLASAFIIL VLMGTWAFLA AGGSCRSLKL
241: CLLCQDKNFL LYNQRSR