1.A.121.1.2 Anterior pharynx-defective 1A (APH-1A) of 265 aas and 7 TMSs in a 3 + 4 TMS arrangement (Dehury and Kepp 2020). See family description for details.
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Accession Number: | Q96BI3 |
Protein Name: | Gamma-secretase subunit APH-1A |
Length: | 265 |
Molecular Weight: | 28996.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 7 |
Location1 / Topology2 / Orientation3: |
Endoplasmic reticulum membrane1 / Multi-pass membrane protein2 |
Substrate |
water |
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1: MGAAVFFGCT FVAFGPAFAL FLITVAGDPL RVIILVAGAF FWLVSLLLAS VVWFILVHVT
61: DRSDARLQYG LLIFGAAVSV LLQEVFRFAY YKLLKKADEG LASLSEDGRS PISIRQMAYV
121: SGLSFGIISG VFSVINILAD ALGPGVVGIH GDSPYYFLTS AFLTAAIILL HTFWGVVFFD
181: ACERRRYWAL GLVVGSHLLT SGLTFLNPWY EASLLPIYAV TVSMGLWAFI TAGGSLRSIQ
241: RSLLCRRQED SRVMVYSALR IPPED