| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
1.A.130.1.1 | Nortia (Nta), the Ca2+ channel protein of 895 aas and ~ 10 TMSs in a 1 + 1 + 2 + 6 [2 + 2 + 2) TMS arrangement (O22752); Feronia (Fer) a receptor-like kinase and constituent of a transmembrane calmodulin-gated calcium (Ca2+) channel protein complexof 542 aas, an MLO-like protein, and Lorleei (Lre, glycosyl PI anchor protein of 165 aas with 2 TMSs, one N-terminal and one C-terminal (B3GS44) (Gao et al. 2022). The channel protein (Nortia) functions in conjunction with these two other proteins, Feronia (Fer), a receptor-like protein kinase, and Lorelei (Lre), a GPI-anchored protein. See the family description, paragraph 1 and Gao et al. 2022 for more details. Two pollen-tube-derived small peptides that belong to the rapid alkalinzation factor (RALF) family seem to be ligands for the FER-LRE co-receptor, which in turn recruits NTA to the plasm membrane. NTA initiates Ca2+ spiking in the synergid cells, for pollen tube reception. Thus, the FER-LRE-NTA complex forms a receptor-channel complex in the female cell to recognize male signals and trigger tertilization. | Eukaryota |
Viridiplantae, Streptophyta | Nta (Nortia) of Arabidopsis thaliana (O22752) Fer (Feronia) (Q9SCZ4) Lre (Lorelei) (B3GS44) |
|
1.A.130.1.2 | Uncharacteerized protein of 489 aas and possibly 8 TMSs in a 3 + 3 + 2 TMS arrangement. | Eukaryota |
Viridiplantae, Streptophyta | UP of Malus baccata |
|
1.A.130.1.3 | Uncharacterized protein of 471 aas and about 8 TMSs, possibly in a 1 + 3 + 1 + 3 TMS arramgement. | Eukaryota |
Viridiplantae, Streptophyta | UP of Zingiber officinale |
|
1.A.130.1.4 | Uncharacterized protein of 570 aas and possibly 7 TMSs in a 3 + 4 TMS arrangement. | Eukaryota |
Viridiplantae, Streptophyta | UP of
Kingdonia uniflora |
|
1.A.130.1.5 | Uncharacterized protein of 1177 aas and possibly 7 TMSs in a 2 + 1 + 2 + 2 TMS arrangement. | Eukaryota |
Viridiplantae, Chlorophyta | UP of Volvox africanus |
|
1.A.130.1.6 | Uncharacterized protein of 1346 aas and about 8 TMSs in a 4 + 4 TMS arrangement. | Eukaryota |
Viridiplantae, Streptophyta | UP of Digitaria exilis |
|
1.A.130.1.7 | MLO 11 of 762 aas and about 7 TMSs in a 1 + 1 + 2 + 3 TMS arrangement.
| Eukaryota |
Viridiplantae, Chlorophyta | MLO11 of Chlorella sorokiniana |
|
1.A.130.1.8 | MLO13 of 630 aas and 7 TMSs in a 3 + 2 + 2 TMS arrangement. | Eukaryota |
Viridiplantae, Chlorophyta | MLO13 of Scenedesmus sp. PABB004 |
|
1.A.130.1.9 | Uncharacterized protein of 617 aas and 7 or 8 TMSs in a 2 + 1 (+ 1) + 2 + 2 TMS arrangement. | Eukaryota |
Viridiplantae, Streptophyta | UP of Papaver somniferum (opium poppy) |
|
1.A.130.1.10 | Uncharacterized protein of 558 aas and possibly 8 TMSs in a 5 + 3 TMS arrangement. | Eukaryota |
Viridiplantae, Streptophyta | UP of Tanacetum cinerariifolium |
|
1.A.130.1.11 | Protein MLO of 533 aas with 7 TMSs in a 1 + 1 + 1 + 2 + 2 TMS arrangement. | Eukaryota |
Viridiplantae, Streptophyta | MLO of Hordeum vulgare (Barley |
|
1.A.130.1.12 | MLO-like protein 5 of 501 aas and 7 TMSs in a 1 + 1 + 1 + 2 + 2 TMS arrangement. It may be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca2+-dependent calmodulin binding and seems not to require heterotrimeric G proteins. | Eukaryota |
Viridiplantae, Streptophyta | MLO5 of Arabidopsis thaliana |
|
1.A.130.1.13 | MLO12 of 1080 aas with 8 TMSs in a 2 + 1 + 4 + 1 TMS arrangement. | Eukaryota |
Viridiplantae, Chlorophyta | MLO12 of Micractinium conductrix |
|
1.A.130.1.14 | EF hand domain-containing protein of 465 aas and 7 TMSs in a 1 + 2 + 1 + 2 + 1 TMS arrangement. | Eukaryota |
Apicomplexa | EF hand protein of Besnoitia besnoiti |
|
1.A.130.1.15 | Uncharacterized protein of 568 aas and 7 TMSs in a 2 + 1 + 4 TMS arrangement. | Eukaryota |
Viridiplantae, Chlorophyta | UP of Monoraphidium neglectum |
|
1.A.130.1.16 | Uncharacterized protein of 716 aas with 8 TMSs in a 4 + 2 + 2 TMS arrangement. | Eukaryota |
Apicomplexa | UP of Toxoplasma gondii |
|
1.A.130.1.17 | Calcium binding protein, putative, of 798 aas and 9 TMSs in a 4 + 3 + 2 TMS arrangement. | Eukaryota |
Perkinsozoa | CBP of Perkinsus marinus |
|
1.A.130.2.1 | Uncharacterized protein of 1348 aas and 14 TMSs with a 3 + 2 + 2 + 3 + 2 + 2 TMS arrangement, clearly indicating an internal 7 TMS duplication. This protein and members of subfamily 1.A.130.2 are Stramenopiles of Sar. | Eukaryota |
Oomycota | UP of Bremia lactucae (lettuce downy mildew) |
|
1.A.130.2.2 | EF-hand domain pair of 16 probable TMSs in a 3 + 2 + 1 +1 + 1 + 3 + 2 + 2 + 1 TMS arrangement. | Eukaryota |
Oomycota | EF hand protein of Phytophthora cactorum |
|
1.A.130.2.3 | EF-hand domain pair of 2457 aas and 18 TMSs in a 2 + 2 + 2 + 3 + 2 + 2 + 2 + 3 TMS arrangement. | Eukaryota |
Oomycota | EF-hand protein of Phytophthora cactorum |
|
1.A.130.2.4 | Uncharacterized protein of 639 aas and 7 TMSs in a 1 + 1 + 3 + 2 TMS arrangement. | Eukaryota |
Oomycota | UP of Aphanomyces invadans |
|
1.A.130.2.5 | Uncharacterized protein of563 aas and 7 TMSs in a 3 + 2 + 2 TMS arrangement. | Eukaryota |
Oomycota | UP of Aphanomyces stellatus |
|
1.A.130.2.6 | Uncharacterized protein of 1034 aas and 7 or 8 TMSs in a 3 + 1 +1 (+1) + 2 + 2 TMS arrangement. | Eukaryota |
UP of Tribonema minus |