TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.A.141.1.1









Effector domain protein of 363 aas with two domains, an N-terminal domain of 90 aas and 2 TMSs (residues 24 - 46 and 66 - 88) and the cyclic nucleotide binding domain of the larger C-terminal domain with three moderately hydrophobic peaks that could be TMSs. The N-terminal response domain is a chloride (Cl-) channel domain (Tak et al. 2023).

Bacteria
Pseudomonadota
Chloride channel protein domain, N-terminus of AOW71412.1 from Enterobacter cloacae
1.A.141.1.2









SAVED domain-containing protein of 355 aas and 2 N-terminal TMSs. The SAVED domain is the cyclic nucleotide binding domain while the N-terminal domain is the chloride (Cl-) channel domain.

Bacteria
Pseudomonadota
SAVED domain protein of E. coli
1.A.141.1.3









SAVED domain-containing protein of 538 aas and 2 or 3 TMSs, the first two in the N-terminal domain (putative Cl- channel domain) and the C-terminal SAVED domain for binding cyclic nucleotide(s).

Bacteria
Terrabacteria group
SAVED domain protein of Nostoc sp. 'Peltigera membranacea cyanobiont' N6
1.A.141.1.4









SAVED domain-containing protein of 338 aas and 2 or 3 TMSs.

Bacteria
Bacillota
SAVED domain protein of Brevibacillus agri
1.A.141.1.5









Uncharacterized protein of 314 aas and 2 - 4 TMSs, two N-terminal and two more possible TMSs in the C-terminal region of the protein.

Archaea
Candidatus Heimdallarchaeota
UP of Candidatus Heimdallarchaeota archaeon LC_3