TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.A.147.1.1









Cam1 - CRISPR effector, shown to depoloarized the cell when activated, protecting against phage infectiions (Baca et al. 2024).  It is 206 aas long with 1 - 3 TMSs.  The N-terminal TMS is very hydrophobic while the second and third possible TMSs are less so.  See family description for details.

Eukaryota
Metazoa, Cnidaria
Cam1 of Entacmaea quadricolor (Bubble-tip sanemone) (Parasicyonis actinostolodes)  
1.A.147.1.2









Uncharacterized protein of 248 aas and1 N-terminal TMS. 

Bacteria
Nitrospirota
UP of Thermodesulfovibrio islandicus
1.A.147.1.3









DUF6293 family protein of 112 aas and possibly 1 N-terminal TMS.

Bacteria
Bacillota
DUF6293 family protein of 212 aas and 1 N-terminal TMS.
1.A.147.1.4









DUF1887 family CARF protein of 371 aas and 0 or 1 N-terminal TMS.

 

Bacteria
Pseudomonadota
DUF1887 family protein of Neisseria dentiae
1.A.147.1.5









TIGR02710 family CRISPR-associated protein of 478 aas and 1 - 4 TMSs. The region of homology with other members of the family is at the N-terminus of this protein.

Bacteria
Chloroflexota
TIGR2710 protein of Herpetosiphonaceae bacterium
1.A.147.1.6









Uncharacterized protein of 274 aas and 3 TMSs, 2 near the N-terminus and1 near the C-termnus.

Bacteria
Pseudomonadota
UP of Thiohalocapsa sp.
1.A.147.1.7









DUF1887 family CARF protein of 386 aas with 1 N-terminal TMS and possibly 1 or 2 more TMSs.

Bacteria
Pseudomonadota
DUF1887 protein of Dongiaceae bacterium
1.A.147.1.8









Uncharacterized protein VSS75_32315 of 259 aas and 2 N-terminal TMSs plus possibly one more TMS.

          
Bacteria
Pseudomonadota
UP of Candidatus Parabeggiatoa sp.
1.A.147.1.9









Uncharacterized CRISPR-associated protein (Cas_Cas02710) of 216 aas with 2 N-terminal TMSs plus one more TMS to the right of the 2 N-terminal TMSs.

Archaea
UP of uncultured archaeon
1.A.147.1.10









Uncharacterized TIGR02710 family CRISPR-associated protein of 569 aas and 1 N-terminal TMS.

Archaea
Candidatus Helarchaeota
UP of Candidatus Helarchaeota archaeon