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1.A.17.1.27
Anoctamin 7, ANO7, or TMEM16G, of 933 aas and 10 TMSs.  It has calcium-dependent phospholipid scramblase activity, scrambling phosphatidylserine, phosphatidylcholine and galactosylceramide, but it does not exhibit calcium-activated chloride channel (CaCC) activity. It may play a role in cell-cell interactions (Das et al. 2008). ANO7 is associated with aggressive prostate cancer (Kaikkonen et al. 2018). Insights into the topology and function of Ano7 have been described (Guo et al. 2021).  

Accession Number:Q6IWH7
Protein Name:Anoctamin-7
Length:933
Molecular Weight:105532.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRMAATAWAG LQGPPLPTLC PAVRTGLYCR DQAHAERWAM TSETSSGSHC ARSRMLRRRA 
61:	QEEDSTVLID VSPPEAEKRG SYGSTAHASE PGGQQAAACR AGSPAKPRIA DFVLVWEEDL 
121:	KLDRQQDSAA RDRTDMHRTW RETFLDNLRA AGLCVDQQDV QDGNTTVHYA LLSASWAVLC 
181:	YYAEDLRLKL PLQELPNQAS NWSAGLLAWL GIPNVLLEVV PDVPPEYYSC RFRVNKLPRF 
241:	LGSDNQDTFF TSTKRHQILF EILAKTPYGH EKKNLLGIHQ LLAEGVLSAA FPLHDGPFKT 
301:	PPEGPQAPRL NQRQVLFQHW ARWGKWNKYQ PLDHVRRYFG EKVALYFAWL GFYTGWLLPA 
361:	AVVGTLVFLV GCFLVFSDIP TQELCGSKDS FEMCPLCLDC PFWLLSSACA LAQAGRLFDH 
421:	GGTVFFSLFM ALWAVLLLEY WKRKSATLAY RWDCSDYEDT EERPRPQFAA SAPMTAPNPI 
481:	TGEDEPYFPE RSRARRMLAG SVVIVVMVAV VVMCLVSIIL YRAIMAIVVS RSGNTLLAAW 
541:	ASRIASLTGS VVNLVFILIL SKIYVSLAHV LTRWEMHRTQ TKFEDAFTLK VFIFQFVNFY 
601:	SSPVYIAFFK GRFVGYPGNY HTLFGVRNEE CAAGGCLIEL AQELLVIMVG KQVINNMQEV 
661:	LIPKLKGWWQ KFRLRSKKRK AGASAGASQG PWEDDYELVP CEGLFDEYLE MVLQFGFVTI 
721:	FVAACPLAPL FALLNNWVEI RLDARKFVCE YRRPVAERAQ DIGIWFHILA GLTHLAVISN 
781:	AFLLAFSSDF LPRAYYRWTR AHDLRGFLNF TLARAPSSFA AAHNRTCRYR AFRDDDGHYS 
841:	QTYWNLLAIR LAFVIVFEHV VFSVGRLLDL LVPDIPESVE IKVKREYYLA KQALAENEVL 
901:	FGTNGTKDEQ PEGSELSSHW TPFTVPKASQ LQQ