1.A.17.4.17
Transmembrane channel-like protein 1 of 878 aas and ~ 11 TMSs (Erives and Fritzsch 2019). Mechanosensory transduction (MT) in specialized hair cells of the inner ear may be mediated by TMC1 as the pore component. Other components of the MT complex include protocadherin 15, cadherin 23, lipoma HMGIC fusion partner-like 5, transmembrane inner ear, calcium and integrin-binding family member 2, and ankyrins (Zheng and Holt 2020).
|
| Accession Number: | XP_019849899.1 |
|---|
| Protein Name: | XP_019849899.1 PREDICTED: transmembrane channel-like protein 1 [Amphimedon queenslandica] |
|---|
| Length: | 879 |
|---|
| Molecular Weight: | |
|---|
| Species: | Amphimedon queenslandica [400682] |
|---|
| Number of TMSs: | 12 |
|---|
| Substrate |
inorganic ion |
|---|
1: MDRHRESSHE QRQRQKMSRT GLSRAGMSES EFMARQRYLE NSSTRAISDH SMAVASQPVI
61: PQLLSSNEVH KYVKEQREII NNFRSQPWPM QMKMAALMMY KENVAVYAGQ MNTLDTFKDN
121: FSIATGAFRR RFRNIRSSLT IWNSIIKRIE GRFGSSVASF FNFLRWLCAL NLIMSFIILA
181: FLVLPQASSG HGLQVPAQIR ENGSPLSFIV DGKGYLLEYS VLFHGFYDSG KNEPYVAPPH
241: NPNPAIGTGY KLPLAYLGVI AAIFVVCILA ILVRMVKKYK ILQKASISEQ YLFAWKVFAS
301: WDFTITSHET AVYKRLRLTT LLKETIVEAD SNDRQTSWKL IVIRLAVHVV LFILLCASAY
361: AIYLAVENID YSTVSVNFVD ALKLGLKGIW LIMRSFQVQA VIVTCNFVFP IMFQVAQLIE
421: QHHPRTALKV MLARLFVLYI TSLYVLIIAL FTFNRTCENT TTVLTNATFI DSDENYCCWE
481: TVMGQELYKL SITHFFAELF SIAVVDIARW IAVKTYICPR ISEKFGLAEF NLARNILKLV
541: YGQALVWFGV LFCPLLPIIN LLKYILLFYI RALVVSLFNK PPQTLFRVAS TKTFYMALLL
601: LNIFLCIFPI SYAVIQEVPS TTCGPFRGLP SMSHAVTYEI DRWPVIIQTV VNYVNTPTII
661: IPLIGLLCIV ISYFASLANA LKEVNKDLRL QLHLELKAAR DKIYRDAIKL KKQDTESEDL
721: SSFSLIRRHE QLQQELNSEL TQRFSKTSNT MFSYVRPFEQ VQINDSFASG SSSSDSSRIR
781: SDNYTDISTL PRIQASTDIE NDELPVTVST FLPPKNKETL KHHQSAEKER SQQDSEGSVN
841: PQRRHYSAPT PQITVGFVNS IHGRPRSRST PLWTSNQK