1.A.17.5.11
Osmotically-gated calcium conductance channel of 782 aas. CSC1 (Hou et al. 2014). Activated under hyperosmotic conditions. There are four paralogues in S. cerevisiae.
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| Accession Number: | Q06538 |
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| Protein Name: | Calcium permeable stress-gated cation channel 1 |
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| Length: | 782 |
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| Molecular Weight: | 89344.00 |
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| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
calcium(2+) |
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1: MTSYIERLKS AASYLDTVPD EHHDFRKPTA KVVTTQLTIA TSLGIFALLS FSILLKKWPR
61: LYASRRYKDD GNLRLPSWNQ SSLFGWLTVL YKIRDEQILE YAGLDAYVFL SFFKMCIKLL
121: SIFCFFSVCV ISPVRYHFTG KIDDGNDDDD SESSLIHLVK RIVEGSGDGD NHSAPERTNV
181: YLWMYVLFTY FFTFIAIKMA VAETKHVVST RQAYLGKQNT ITDRTIRLSG IPIELRDSEA
241: LKTRIEQLKI GTVSSITICR EWGPLNKLFH CRKKILKNLE LKYSECPREL RTRQPYSENY
301: HLLGNEQSGA VTHGENVPSS NNNDEDTILY SQISLGERPK MKIGYRGIFG KEVDAIEYLE
361: QQLKFIDAEI IEARKQHYSA TPTAFVTMDS VANAQMAAQA VLDPRVHYFI TRLAPAPHDI
421: KWDHVCLSRK DRLTKVYSTT VFIGLSSLFL VIPVSYLATL LNLKTLSKFW PSVGQLLKDH
481: QWAANIVTGL LPTYLFTLLN FGIPYFYEYL TSYQGLVSYS EEEISLVSKN FFYIFVNLFL
541: VFTLAGTASN YWAYLSDTTK IAYQLATSVK EFSLFYVDLI ILQGIGMFPF KLLLVGSLIG
601: FPLVKIKAKT PRQRNELYNP PIFNFGLQLP QPILILIITL IYSVMSTKIL TSGLAYFIIG
661: FYVYKYQLIF ATDHLPHSTG KVWPLIFRRI IVGLLLFQLT MTGTLAGFEG GWVLSSCLFP
721: LPVVTLCFLY DFEKNYLPLS KYIALSSIRE YERDNSTVNS ANEEESYAYP YAVSELEGPM
781: LD