1.A.21.1.5
Pro-survival Bcl-w protein. Binds the BH3-only protein Bop to inhibit Bop-induced apoptosis (Zhang et al. 2012). The structure is known (PDB# 1MK3).
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Accession Number: | Q92843 |
Protein Name: | Bcl-2-like protein 2 |
Length: | 193 |
Molecular Weight: | 20746.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Mitochondrion membrane1 / Peripheral membrane protein2 |
Substrate |
cytochrome c |
---|
1: MATPASAPDT RALVADFVGY KLRQKGYVCG AGPGEGPAAD PLHQAMRAAG DEFETRFRRT
61: FSDLAAQLHV TPGSAQQRFT QVSDELFQGG PNWGRLVAFF VFGAALCAES VNKEMEPLVG
121: QVQEWMVAYL ETQLADWIHS SGGWAEFTAL YGDGALEEAR RLREGNWASV RTVLTGAVAL
181: GALVTVGAFF ASK