TCDB » SEARCH

« See all members of the family

1.A.26.2.2 Mg²⁺ transporter, SLC41A2 (11 TMSs with the N-terminus out and the C-terminus in) (Sahni et al. 2007). (63% identical to SLC41A1) See also (Wabakken et al., 2003; Schmitz et al., 2007)
Accession Number:	Q96JW4
Protein Name:	SLC41A2
Length:	573
Molecular Weight:	62473.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	10
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	magnesium(2+)

RefSeq:	NP_115524.3
Entrez Gene ID:	84102
Pfam:	PF01769
OMIM:	610802 gene
KEGG:	hsa:84102 hsa:84102 hsa:84102
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0008324 F:cation transmembrane transporter activity GO:0006812 P:cation transport GO:0055085 P:transmembrane transport
References (12) [1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [3] “Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.” Wiemann S.et.al. 11230166 [4] “SLC41A2 encodes a plasma-membrane Mg2+ transporter.” Sahni J.et.al. 16984228 [5] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [7] “Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.” Wiemann S.et.al. 11230166 [8] “SLC41A2 encodes a plasma-membrane Mg2+ transporter.” Sahni J.et.al. 16984228 [9] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [10] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [11] “Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.” Wiemann S.et.al. 11230166 [12] “SLC41A2 encodes a plasma-membrane Mg2+ transporter.” Sahni J.et.al. 16984228

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MTNSKGRSIT DKTSGGPSSG GGFVDWTLRL NTIQSDKFLN LLLSMVPVIY QKNQEDRHKK 
61:	ANGIWQDGLS TAVQTFSNRS EQHMEYHSFS EQSFHANNGH ASSSCSQKYD DYANYNYCDG 
121:	RETSETTAML QDEDISSDGD EDAIVEVTPK LPKESSGIMA LQILVPFLLA GFGTVSAGMV 
181:	LDIVQHWEVF RKVTEVFILV PALLGLKGNL EMTLASRLST AVNIGKMDSP IEKWNLIIGN 
241:	LALKQVQATV VGFLAAVAAI ILGWIPEGKY YLDHSILLCS SSVATAFIAS LLQGIIMVGV 
301:	IVGSKKTGIN PDNVATPIAA SFGDLITLAI LAWISQGLYS CLETYYYISP LVGVFFLALT 
361:	PIWIIIAAKH PATRTVLHSG WEPVITAMVI SSIGGLILDT TVSDPNLVGI VVYTPVINGI 
421:	GGNLVAIQAS RISTYLHLHS IPGELPDEPK GCYYPFRTFF GPGVNNKSAQ VLLLLVIPGH 
481:	LIFLYTIHLM KSGHTSLTII FIVVYLFGAV LQVFTLLWIA DWMVHHFWRK GKDPDSFSIP 
541:	YLTALGDLLG TALLALSFHF LWLIGDRDGD VGD

1.A.26.2.2
Mg²⁺ transporter, SLC41A2 (11 TMSs with the N-terminus out and the C-terminus in) (Sahni et al. 2007). (63% identical to SLC41A1) See also (Wabakken et al., 2003; Schmitz et al., 2007)

Cross database links:

Gene Ontology

References (12)

External Searches:

Analyze:

1.A.26.2.2Mg2+ transporter, SLC41A2 (11 TMSs with the N-terminus out and the C-terminus in) (Sahni et al. 2007). (63% identical to SLC41A1) See also (Wabakken et al., 2003; Schmitz et al., 2007)

Cross database links:

Gene Ontology

References (12)

External Searches:

Analyze:

1.A.26.2.2
Mg²⁺ transporter, SLC41A2 (11 TMSs with the N-terminus out and the C-terminus in) (Sahni et al. 2007). (63% identical to SLC41A1) See also (Wabakken et al., 2003; Schmitz et al., 2007)