| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
1.A.29.1.1 | Putative amide transporter (AmiS) (Wilson et al., 1995). | Bacteria |
Pseudomonadota | AmiS of Pseudomonas aeruginosa |
|
1.A.29.1.2 | Putative amide transporter (AmiS) | Bacteria |
Actinomycetota | AmiS of Rhodococcus erythropolis |
|
1.A.29.1.3 | Proton-gated urea transport channel (UreI) (pH-sensitive). Allows the transmembrane flow of urea, hydroxyurea and (at a low rate) water. KB for urea is ~150mM (Sachs et al., 2006; Scott et al., 2010). Transport kinetics and selectivity have been defined (Gray et al., 2011). The 3-d structure reveals a hexameric protein with a channel included within the twisted 6 TMS bundle of each protomer. It displays a two helix hairpin structure repeated three times around the central axis of the channel (Strugatsky et al. 2012). | Bacteria |
Campylobacterota | UreI of Helicobacter pylori |
|
1.A.29.1.4 | Urea transporter channel (UreI) (pH-insensitive) | Bacteria |
Bacillota | UreI of Streptococcus salivarius |
|
1.A.29.1.5 | Urea transporter channel (UreI) (pH-sensitive) | Bacteria |
Campylobacterota | UreI of Helicobacter hepaticus (AAK69200) |
|
1.A.29.1.6 | The hexameric ring urea/acetamide/small amide channel, UreI (7 TMSs) (Huysmans et al., 2012). | Bacteria |
Bacillota | UreI of Bacillus cereus (Q814I5) |