1.A.35.5.8
MIT1 of 529 aas and 2 C-terminal TMSs. It is a Mg2+/Co2+/Ni2+ ion channel (Wunderlich 2022).
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| Accession Number: | Q8IIG4 |
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| Protein Name: | Mitochondrial inner membrane magnesium transporter MIT1 |
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| Length: | 529 |
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| Molecular Weight: | 63252.00 |
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| Species: | Plasmodium falciparum (isolate 3D7) [36329] |
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| Number of TMSs: | 2 |
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| Location1 / Topology2 / Orientation3: |
Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
magnesium(2+), cobalt(2+), nickel(2+) |
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1: MFVWTHINKY TSRYINRYIL KFTRYESLRL CMLNFTSTIK NENKIYSKKN FNNVLMQNIK
61: ITEDEEIICE QFFFSKYNLP YVLKIPFSDL RLIDTCNNNH NPTILIRKDM ILLRTGFLSC
121: VIRYNELWLF EPREPLVIKA TNLIKQNLKI IYGFKGDMSS GVEIPLNELK DEKCQENVNM
181: YEKNIRNDLY STYEKNISDD INDAKQKNMC SDINNIWSNH IKIDKKRIIS GNYSRLNRNN
241: IWENDREINK KDIFNIKEKK NMNENDDICN KIKIVGKEEL NNNIKEDINY LNVENNFYRY
301: KGNISFEFLC LDICMQLSIK EYENYLDTIN ITLRQKIQLQ QKKEENIEIN MLTNNLLREM
361: MKIKNKLQKL SNLLNALRSN IEKILKNETD MKNMYLTTLN KISINKIKDY SDLEILLETH
421: LQLTDELSGE LENMEEKITH YEELMRLNLD YNRNKFILLN AKISFSTLFC SICAVITSLF
481: GMNLKNFIEH NDYAFFIVSI FITSWSIVGI YFTKNINTLL RFFDKYNVK